Ligand id: 508

Name: corbadrine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 86.71
Molecular weight 183.09
XLogP 0.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used topically as a nasal decongestant and as a vasoconstrictor in dentistry.
Mechanism Of Action and Pharmacodynamic Effects
Agonist of α-adrenoceptors in the nasal mucosa, causing vasoconstriction. However, we have been unable to find affinity data for this drug (at the human target) to substantiate this MMOA.