BPN14770 [Ligand Id: 10451] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499] | ||||||||
| GtoPdb | Inhibition of a fluorescent determination of reaction rate of cAMP hydrolysis by purified human PDE4D7-S129(wt) dimer (basal). | - | 5.99 | pIC50 | 1018 | nM | IC50 | J Med Chem (2019) 62: 4884-4901 [PMID:31013090] |
| GtoPdb | Inhibition of a fluorescent determination of reaction rate of cAMP hydrolysis by purified human PDE4D2 monomer, | - | 6.9 | pIC50 | 127 | nM | IC50 | J Med Chem (2019) 62: 4884-4901 [PMID:31013090] |
| GtoPdb | Inhibition of a fluorescent determination of reaction rate of cAMP hydrolysis by purified human PDE4D7-S129D dimer (activated). | - | 8.11 | pIC50 | 7.8 | nM | IC50 | J Med Chem (2019) 62: 4884-4901 [PMID:31013090] |
| GtoPdb | Inhibition of a fluorescent determination of reaction rate of cAMP hydrolysis by purified human PDE4D3-S54D dimer (activated). | - | 8.13 | pIC50 | 7.4 | nM | IC50 | J Med Chem (2019) 62: 4884-4901 [PMID:31013090] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
