AUY954 [Ligand Id: 2925] activity data from GtoPdb

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  • S1P1 receptor in Human [GtoPdb: 275] [UniProtKB: P21453]
  • S1P1 receptor in Mouse [GtoPdb: 275] [UniProtKB: O08530]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 S1P1 receptor HumanMouse
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  • S1P2 receptor in Mouse [GtoPdb: 276] [UniProtKB: P52592]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 S1P2 receptor Mouse
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  • S1P3 receptor in Mouse [GtoPdb: 277] [UniProtKB: Q9Z0U9]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 S1P3 receptor Mouse
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  • S1P4 receptor in Mouse [GtoPdb: 278] [UniProtKB: Q9Z0L1]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 S1P4 receptor Mouse
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  • S1P5 receptor in Human [GtoPdb: 279] [UniProtKB: Q9H228]
  • S1P5 receptor in Mouse [GtoPdb: 279] [UniProtKB: Q91X56]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 S1P5 receptor HumanMouse
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
S1P1 receptor in Human [GtoPdb: 275] [UniProtKB: P21453]
GtoPdb - - 8.92 pEC50 1.2 nM EC50 Chem Biol (2006) 13: 1227-34 [PMID:17114004]
S1P1 receptor in Mouse [GtoPdb: 275] [UniProtKB: O08530]
GtoPdb - - 9.05 pEC50 0.9 nM EC50 Chem Biol (2006) 13: 1227-34 [PMID:17114004]
S1P2 receptor in Mouse [GtoPdb: 276] [UniProtKB: P52592]
GtoPdb - - 5 pEC50 - - - Chem Biol (2006) 13: 1227-34 [PMID:17114004]
S1P3 receptor in Mouse [GtoPdb: 277] [UniProtKB: Q9Z0U9]
GtoPdb - - 5.96 pEC50 - - - Chem Biol (2006) 13: 1227-34 [PMID:17114004];
Bioorg Med Chem (2007) 15: 663-77 [PMID:17113298]
S1P4 receptor in Mouse [GtoPdb: 278] [UniProtKB: Q9Z0L1]
GtoPdb - - 6 pEC50 - - - Chem Biol (2006) 13: 1227-34 [PMID:17114004]
S1P5 receptor in Human [GtoPdb: 279] [UniProtKB: Q9H228]
GtoPdb - - 6.47 pEC50 340 nM EC50 Chem Biol (2006) 13: 1227-34 [PMID:17114004]
S1P5 receptor in Mouse [GtoPdb: 279] [UniProtKB: Q91X56]
GtoPdb - - 6.5 pEC50 - - - Chem Biol (2006) 13: 1227-34 [PMID:17114004]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.