bermekimab   Click here for help

GtoPdb Ligand ID: 8089

Synonyms: MABp1 | RA-18C3 | Xilonix® (proposed trade name)
Compound class: Antibody
Comment: Bermekimab (MABp1, Xilonix) is an investigational fully human monoclonal antibody targeting IL-1α, with potential antiinflammatory action. This antibody is the first genuinely human monoclonal antibody to be produced directly from an affinity matured, human immune response. As MABp1 has not been subject to in vitro sequence modification it is predicted to have improved tolerability compared to antibodies that are 'humanised'.
A patent search suggests that Xilonix is the subject of WO2009148575 [3].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10806 bermekimab
Synonyms Click here for help
MABp1 | RA-18C3 | Xilonix® (proposed trade name)
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 544
Other databases
GtoPdb PubChem SID 249565769
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