Synonyms: AUY922 | NVP-AUY922
Compound class:
Synthetic organic
Comment: Luminespib (NVP-AUY922) is an intravenous HSP90 inhibitor with the potential to target a range of cancers. Discovered during a research collaboration with Novartis, Vernalis is now looking to partner the programme. We have drawn the structure as depicted in its INN record. Other chemistry resources show alternative tautomers. For example, PubChem CID 10096043 matches on CAS registry number, but is a structural tautomer.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification ![]() |
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Compound class | Synthetic organic |
International Nonproprietary Names ![]() |
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INN number | INN |
9678 | luminespib |
Synonyms ![]() |
AUY922 | NVP-AUY922 |
Database Links ![]() |
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GtoPdb PubChem SID | 315661336 |
PubChem CID | 135539077 |
RCSB PDB Ligand | 2GJ |
Search Google for chemical match using the InChIKey | NDAZATDQFDPQBD-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | NDAZATDQFDPQBD |
Search PubMed clinical trials | luminespib |
Search PubMed titles | luminespib |
Search PubMed titles/abstracts | luminespib |
UniChem Compound Search for chemical match using the InChIKey | NDAZATDQFDPQBD-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | NDAZATDQFDPQBD-UHFFFAOYSA-N |