Synonyms: Betamaze | CP-45,899 | CP-45899
sulbactam is an approved drug (FDA (1986))
Compound class:
Synthetic organic
Comment: Sulbactam is a β-lactamase inhibitor that is used to limit degradation of β-lactam antibacterials. Its synergy with β-lactam antibacterials against some multiply drug-resistant Enterobacteriaceae and Pseudomonas species is reported to be inconsistent, likely as it cannot inhibit the AmpC cephalosporinase expressed by these species [1].
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1986)) |
Approved drug? | Yes. FDA (1986) |
Prodrug | sultamicillin |
IUPAC Name ![]() |
(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
International Nonproprietary Names ![]() |
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INN number | INN |
4845 | sulbactam |
Synonyms ![]() |
Betamaze | CP-45,899 | CP-45899 |
Database Links ![]() |
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Specialist databases | |
Antibiotic DB
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Sulbactam | Sulbactam/ carbenicillin |
Other databases | |
CAS Registry No. | 68373-14-8 (source: WHO INN record) |
ChEMBL Ligand | CHEMBL403 |
DrugCentral Ligand | 2492 |
GtoPdb PubChem SID | 405560210 |
PubChem CID | 130313 |
RCSB PDB Ligand | 0RN |
Search Google for chemical match using the InChIKey | FKENQMMABCRJMK-RITPCOANSA-N |
Search Google for chemicals with the same backbone | FKENQMMABCRJMK |
Search PubMed clinical trials | sulbactam |
Search PubMed titles | sulbactam |
Search PubMed titles/abstracts | sulbactam |
UniChem Compound Search for chemical match using the InChIKey | FKENQMMABCRJMK-RITPCOANSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | FKENQMMABCRJMK-RITPCOANSA-N |
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Sulbactam (links to external site)
Cat. No. HY-B0334 |