cilofexor [Ligand Id: 10644] activity data from GtoPdb

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  • Farnesoid X receptor in Human [GtoPdb: 603] [UniProtKB: Q96RI1]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Farnesoid X receptor in Human [GtoPdb: 603] [UniProtKB: Q96RI1]
GtoPdb EC50 determined as the ability of cilofexor to modulate the interaction between the purified bacterial expressed FXR ligand binding domain (LBD) and a synthetic biotinylated peptide based on residues 676-700 of SRC1, in a TR-FRET assay. - 7.6 pEC50 <25 nM EC50 US10485795B2. FXR (NR1H4) binding and activity modulating compounds (2019)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.