ChEMBL ligand: CHEMBL3186774
egl-9 family hypoxia inducible factor 1/Egl nine homolog 1 in Human [ChEMBL: CHEMBL5697] [GtoPdb: 2833] [UniProtKB: Q9GZT9] There should be some charts here, you may need to enable JavaScript!
Prolyl 4-hydroxylase in Paramecium bursaria Chlorella virus 1 [ChEMBL: CHEMBL4523368] [UniProtKB: Q84406] There should be some charts here, you may need to enable JavaScript!
lysine demethylase 2A in Human [GtoPdb: 2671] [UniProtKB: Q9Y2K7] There should be some charts here, you may need to enable JavaScript!
lysine demethylase 5C in Human [GtoPdb: 2682] [UniProtKB: P41229] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
egl-9 family hypoxia inducible factor 1/Egl nine homolog 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5697] [GtoPdb: 2833] [UniProtKB: Q9GZT9]
ChEMBL	Inhibition of recombinant human PHD2 by alphascreen assay	B	7.66	pIC50	22	nM	IC50	Bioorg Med Chem (2019) 27: 2405-2412 [PMID:30737136]
ChEMBL	Inhibition of human PHD2	B	7.66	pIC50	22	nM	IC50	J Med Chem (2019) 62: 5725-5749 [PMID:30682255]
GtoPdb	-	-	7.66	pIC50	22	nM	IC50	ACS Chem Biol (2013) 8: 1488-96 [PMID:23683440]
Prolyl 4-hydroxylase in Paramecium bursaria Chlorella virus 1 (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4523368] [UniProtKB: Q84406]
ChEMBL	Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-incubated for 5 mins before 2OG as substrate and Fe2 as co-factor addition in presence of L-ascorbate and measured after 5 mins MALDI TOF MS analysis	B	5.07	pIC50	8500	nM	IC50	Bioorg Med Chem (2019) 27: 2405-2412 [PMID:30737136]
lysine demethylase 2A in Human [GtoPdb: 2671] [UniProtKB: Q9Y2K7]
GtoPdb	-	-	7.28	pIC50	52	nM	IC50	ACS Chem Biol (2013) 8: 1488-96 [PMID:23683440]
lysine demethylase 5C in Human [GtoPdb: 2682] [UniProtKB: P41229]
GtoPdb	-	-	6.8	pIC50	159	nM	IC50	ACS Chem Biol (2013) 8: 1488-96 [PMID:23683440]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]