triprolidine   Click here for help

GtoPdb Ligand ID: 1228

Synonyms: Actidil®
Approved drug
triprolidine is an approved drug (FDA (1982))
Compound class: Synthetic organic
Comment: Marketed formulations often contained triprolidine hydrochloride, but many of these have been discontinued.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 16.13
Molecular weight 278.18
XLogP 4.01
No. Lipinski's rules broken 0
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Canonical SMILES Cc1ccc(cc1)C(=CCN1CCCC1)c1ccccn1
Isomeric SMILES Cc1ccc(cc1)/C(=C\CN1CCCC1)/c1ccccn1
InChI InChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3/b18-11+
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1982))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
502 triprolidine
Synonyms Click here for help
Database Links Click here for help
Specialist databases
GPCRdb Ligand triprolidine
Other databases
CAS Registry No. 486-12-4 (source: Scifinder)
DrugBank Ligand DB00427
DrugCentral Ligand 2763
GtoPdb PubChem SID 135651281
PubChem CID 5282443
Search Google for chemical match using the InChIKey CBEQULMOCCWAQT-WOJGMQOQSA-N
Search Google for chemicals with the same backbone CBEQULMOCCWAQT
Search PubMed clinical trials triprolidine
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UniChem Compound Search for chemical match using the InChIKey CBEQULMOCCWAQT-WOJGMQOQSA-N
UniChem Connectivity Search for chemical match using the InChIKey CBEQULMOCCWAQT-WOJGMQOQSA-N
Wikipedia Triprolidine