fludroxycortide   Click here for help

GtoPdb Ligand ID: 7606

Synonyms: Cordran® | flurandrenolide | flurandrenolone | Haelan®
Approved drug Immunopharmacology Ligand
fludroxycortide is an approved drug (FDA (1963))
Compound class: Synthetic organic
Comment: Fludroxycortide is a synthetic topical glucocorticoid, used clinically for its antiinflammatory action [2].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 93.06
Molecular weight 436.23
XLogP 0.65
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OCC(=O)C12OC(OC1CC1C2(C)CC(O)C2C1CC(C1=CC(=O)CCC21C)F)(C)C
Isomeric SMILES OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1C[C@@H](C1=CC(=O)CC[C@]21C)F)(C)C
InChI InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
InChI Key POPFMWWJOGLOIF-XWCQMRHXSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1963))
International Nonproprietary Names Click here for help
INN number INN
1123 fludroxycortide
Synonyms Click here for help
Cordran® | flurandrenolide | flurandrenolone | Haelan®
Database Links Click here for help
CAS Registry No. 1524-88-5 (source: Scifinder)
ChEMBL Ligand CHEMBL1201012
DrugBank Ligand DB00846
DrugCentral Ligand 1217
GtoPdb PubChem SID 223365941
PubChem CID 15209
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Wikipedia Fludroxycortide