pyridostigmine

Ligand id: 8994

Name: pyridostigmine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 33.42
Molecular weight 181.1
XLogP 1.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1955))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
(1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate
International Nonproprietary Names
INN number INN
278 pyridostigmine bromide
Synonyms
Mestinon® | Regonol®
Comments
Pyridostigmine is a peripherally acting, orally active reversible acetylcholinesterase (ACHE) inhibitor, with a slightly longer duration of action than neostigmine. Marketed formulations contain pyridostigmine bromide (PubChem CID 7550).
Database Links
BindingDB Ligand 50313079
CAS Registry No. 155-97-5
ChEMBL Ligand CHEMBL1115
DrugBank Ligand DB00545
GtoPdb PubChem SID 310264772
Immunopaedia Search pyridostigmine
PubChem CID 4991
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Search UniChem for chemical match using the InChIKey RVOLLAQWKVFTGE-UHFFFAOYSA-N
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