pyridostigmine   Click here for help

GtoPdb Ligand ID: 8994

Synonyms: Mestinon® | Regonol®
Approved drug
pyridostigmine is an approved drug (FDA (1955))
Compound class: Synthetic organic
Comment: Pyridostigmine is a peripherally acting, orally active reversible acetylcholinesterase (ACHE) inhibitor, with a slightly longer duration of action than neostigmine. Marketed formulations contain pyridostigmine bromide (PubChem CID 7550).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 33.42
Molecular weight 181.1
XLogP 1.98
No. Lipinski's rules broken 0
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Canonical SMILES C[n+]1cccc(c1)OC(=O)N(C)C
Isomeric SMILES C[n+]1cccc(c1)OC(=O)N(C)C
InChI InChI=1S/C9H13N2O2/c1-10(2)9(12)13-8-5-4-6-11(3)7-8/h4-7H,1-3H3/q+1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1955))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
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IUPAC Name Click here for help
(1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate
International Nonproprietary Names Click here for help
INN number INN
278 pyridostigmine bromide
Synonyms Click here for help
Mestinon® | Regonol®
Database Links Click here for help
Specialist databases
Reactome Drug Reactome logo R-ALL-9634956
Reactome Reaction Reactome logo R-HSA-9634834
Other databases
BindingDB Ligand 50313079
CAS Registry No. 155-97-5
ChEMBL Ligand CHEMBL1115
DrugBank Ligand DB00545
DrugCentral Ligand 2330
GtoPdb PubChem SID 310264772
Immunopaedia Search pyridostigmine
PubChem CID 4991
Search Google for chemical match using the InChIKey RVOLLAQWKVFTGE-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey RVOLLAQWKVFTGE-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey RVOLLAQWKVFTGE-UHFFFAOYSA-N