neostigmine

Ligand id: 8993

Name: neostigmine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 29.54
Molecular weight 223.14
XLogP 1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA)
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium
International Nonproprietary Names
INN number INN
401 neostigmine bromide
Synonyms
Prostigmin®
Comments
Neostigmine is a peripherally acting, reversible acetylcholinesterase (ACHE) inhibitor. Marketed formulations contain neostigmine bromide (PubChem CID 8246) or neostigmine methylsulfate (CID 5824).
Database Links
BindingDB Ligand 50022775
CAS Registry No. 59-99-4
ChEMBL Ligand CHEMBL278020
DrugBank Ligand DB01400
GtoPdb PubChem SID 310264771
PubChem CID 4456
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Search UniChem for chemicals with the same backbone ALWKGYPQUAPLQC