pyridostigmine   Click here for help

GtoPdb Ligand ID: 8994

Synonyms: Mestinon® | Regonol®
Approved drug
pyridostigmine is an approved drug (FDA (1955))
Compound class: Synthetic organic
Comment: Pyridostigmine is a peripherally acting, orally active reversible acetylcholinesterase (ACHE) inhibitor, with a slightly longer duration of action than neostigmine. Marketed formulations contain pyridostigmine bromide (PubChem CID 7550).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 33.42
Molecular weight 181.1
XLogP 1.98
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES C[n+]1cccc(c1)OC(=O)N(C)C
Isomeric SMILES C[n+]1cccc(c1)OC(=O)N(C)C
InChI InChI=1S/C9H13N2O2/c1-10(2)9(12)13-8-5-4-6-11(3)7-8/h4-7H,1-3H3/q+1
InChI Key RVOLLAQWKVFTGE-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1955))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
(1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate
International Nonproprietary Names Click here for help
INN number INN
278 pyridostigmine bromide
Synonyms Click here for help
Mestinon® | Regonol®
Database Links Click here for help
Specialist databases
Reactome Drug Reactome logo R-ALL-9634956
Reactome Reaction Reactome logo R-HSA-9634834
Other databases
BindingDB Ligand 50313079
CAS Registry No. 155-97-5
ChEMBL Ligand CHEMBL1115
DrugBank Ligand DB00545
DrugCentral Ligand 2330
GtoPdb PubChem SID 310264772
Immunopaedia Search pyridostigmine
PubChem CID 4991
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