vidupiprant

Ligand id: 10169

Name: vidupiprant

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 130.18
Molecular weight 608.1
XLogP 6.8
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[4-[4-(tert-butylcarbamoyl)-2-[(2-chloro-4-cyclopropylphenyl)sulfonylamino]phenoxy]-5-chloro-2-fluorophenyl]acetic acid
International Nonproprietary Names
INN number INN
9387 vidupiprant
Synonyms
AMG 853 | AMG-853 | AMG853 | compound 2 [PMID: 24900313]
Comments
Vidupiprant (AMG853) is a dual prostanoid DP1 and DP2 receptor antagonist that was developed for anti-asthmatic potential [2].
Database Links
BindingDB Ligand 50363928
CAS Registry No. 1169483-24-2 (source: PubChem)
ChEMBL Ligand CHEMBL1951575
GtoPdb PubChem SID 381118879
PubChem CID 42641863
Search Google for chemical match using the InChIKey PFWVGKROPKKEDW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PFWVGKROPKKEDW
Search PubMed clinical trials vidupiprant
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Search UniChem for chemical match using the InChIKey PFWVGKROPKKEDW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PFWVGKROPKKEDW

Product suppliers

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Tocris
AMG 853
Cat. No. 5701