urotensin II-related peptide [Ligand Id: 2156] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL437110
  • UT receptor/Urotensin II receptor in Human [ChEMBL: CHEMBL3764] [GtoPdb: 365] [UniProtKB: Q9UKP6]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
UT receptor/Urotensin II receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3764] [GtoPdb: 365] [UniProtKB: Q9UKP6]
GtoPdb - - 9.6 pKd 0.24 nM Kd Peptides (2008) 29: 809-12 [PMID:17628210];
J Neurochem (2008) 107: 361-74 [PMID:18710417]
ChEMBL Displacement of [125I]human urotensin-2 from human GPR14 transfected in CHO cells B 6.58 pKi 263.03 nM Ki J. Med. Chem. (2006) 49: 7234-7238 [PMID:17125276]
GtoPdb - - 8.6 pIC50 - - - Biochem Biophys Res Commun (2003) 310: 860-8 [PMID:14550283]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]