pegvisomant   Click here for help

GtoPdb Ligand ID: 7485

Synonyms: B2036-PEG | Somavert®
Approved drug
pegvisomant is an approved drug (FDA (2003), EMA (2008))
Comment: Pegvisomant is a PEGylated 191 amino acid protein analogue of growth hormone, with antagonist action at the growth hormone receptor. The peptide sequence can be obtained via the ChEMBL link. PEGylation protects the peptide from proteolytic breakdown and extends its bioactive half-life.
Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (FDA (2003), EMA (2008))
International Nonproprietary Names Click here for help
INN number INN
7941 pegvisomant
Synonyms Click here for help
B2036-PEG | Somavert®
Database Links Click here for help
ChEMBL Ligand CHEMBL1201515
DrugBank Ligand DB00082
GtoPdb PubChem SID 187051788
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Wikipedia Pegvisomant