IFN-β1a (recombinant human)   Click here for help

GtoPdb Ligand ID: 8339

Synonyms: Avonex® | Rebif®
Approved drug
IFN-β1a (recombinant human) is an approved drug (FDA (1996), EMA (1997))
Compound class: Peptide or derivative
Comment: Compared to the sequence of the endogenous peptide, IFN-β1a has a Gln to Cys substitution at position 17 and retains the Asn glycosylation site at position 80. Whilst the regular form of this peptide has to be injected 1-3 times/week, a PEGylated form (peginterferon beta-1a) is now available that requires less frequent administration (on a fortnightly basis).
Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (FDA (1996), EMA (1997))
International Nonproprietary Names Click here for help
INN number INN
5380 interferon beta
Synonyms Click here for help
Avonex® | Rebif®
Database Links Click here for help
DrugBank Ligand DB00060
GtoPdb PubChem SID 252166551
Search PubMed clinical trials interferon beta
Search PubMed titles interferon beta
Search PubMed titles/abstracts interferon beta
Wikipedia Interferon_beta_1a