Mg2+ [Ligand Id: 708] activity data from GtoPdb

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  • CaS receptor in Rat [GtoPdb: 54] [UniProtKB: P48442]
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  • HCN1 in Mouse [GtoPdb: 400] [UniProtKB: O88704]
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  • HCN2 in Mouse [GtoPdb: 401] [UniProtKB: O88703]
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  • Kir1.1 in Rat [GtoPdb: 429] [UniProtKB: P35560]
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  • Kir2.1 in Mouse [GtoPdb: 430] [UniProtKB: P35561]
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  • Kir2.2 in Human [GtoPdb: 431] [UniProtKB: Q14500]
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  • Kir2.3 in Human [GtoPdb: 432] [UniProtKB: P48050]
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  • TRPC5 in Rat [GtoPdb: 490]
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  • TRPM3 in Mouse [GtoPdb: 495]
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  • TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84]
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  • TRPM7 in Mouse [GtoPdb: 499] [UniProtKB: Q923J1]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CaS receptor in Rat [GtoPdb: 54] [UniProtKB: P48442]
GtoPdb - - 2.4 pKd - - - Proc. Natl. Acad. Sci. U.S.A. (1995) 92: 131-5 [PMID:7816802];
Bone Miner (1989) 5: 249-57 [PMID:2655774]
HCN1 in Mouse [GtoPdb: 400] [UniProtKB: O88704]
GtoPdb - - 3.3 pIC50 - - - Am. J. Physiol., Cell Physiol. (2008) 295: C557-65 [PMID:18579800]
HCN2 in Mouse [GtoPdb: 401] [UniProtKB: O88703]
GtoPdb - - 3.2 pIC50 - - - Am. J. Physiol., Cell Physiol. (2008) 295: C557-65 [PMID:18579800]
Kir1.1 in Rat [GtoPdb: 429] [UniProtKB: P35560]
GtoPdb - - 2.2 pKi 6000000 nM Ki J. Am. Soc. Nephrol. (2010) 21: 2109-16 [PMID:21030597]
GtoPdb - - 2.3 pKi 5000000 nM Ki J. Am. Soc. Nephrol. (2010) 21: 2109-16 [PMID:21030597];
J. Physiol. (Lond.) (1994) 476: 399-409 [PMID:8057249]
Kir2.1 in Mouse [GtoPdb: 430] [UniProtKB: P35561]
GtoPdb - - 4.8 pKd 17100 nM Kd Neuron (1995) 14: 1047-54 [PMID:7748552]
Kir2.2 in Human [GtoPdb: 431] [UniProtKB: Q14500]
GtoPdb - - 4.96 pIC50 11000 nM IC50 J. Physiol. (Lond.) (1996) 493 ( Pt 1): 143-56 [PMID:8735700]
Kir2.3 in Human [GtoPdb: 432] [UniProtKB: P48050]
GtoPdb - - 5 pKd 10000 nM Kd Nature (1994) 372: 366-9 [PMID:7969496]
TRPC5 in Rat [GtoPdb: 490]
GtoPdb - - 3.34 pIC50 - - - J. Neurosci. (2005) 25: 1234-9 [PMID:15689561]
TRPM3 in Mouse [GtoPdb: 495]
GtoPdb - - 2 pIC50 - - - J. Biol. Chem. (2005) 280: 22540-8 [PMID:15824111]
TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84]
GtoPdb - - 3.3 pIC50 - - - J. Biol. Chem. (2004) 279: 19-25 [PMID:14576148]
GtoPdb - - 6 pIC50 1100 nM IC50
TRPM7 in Mouse [GtoPdb: 499] [UniProtKB: Q923J1]
GtoPdb - - 2.49 pIC50 3200000 nM IC50 Nature (2001) 411: 590-5 [PMID:11385574]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.