L-(cis)-diltiazem [Ligand Id: 2349] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1397935 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CNGA1 in Human [GtoPdb: 394] [UniProtKB: P29973] | ||||||||
| GtoPdb | - | - | 4 | pKi | 100000 | nM | Ki | Nature (1993) 362: 764-7 [PMID:7682292] |
| CNGA2 in Rat [GtoPdb: 395] [UniProtKB: Q00195] | ||||||||
| GtoPdb | - | - | 2.12 | pKi | - | - | - | Nature (1990) 347: 184-7 [PMID:1697649] |
| CNGB3 in Mouse [GtoPdb: 399] [UniProtKB: Q9JJZ9] | ||||||||
| GtoPdb | - | - | 5.5 | pIC50 | - | - | - | J Neurosci (2000) 20: 1324-32 [PMID:10662822] |
| Cav1.4 in Mouse [GtoPdb: 531] [UniProtKB: Q9JIS7] | ||||||||
| GtoPdb | - | - | 4.1 | pIC50 | - | - | - | Invest Ophthalmol Vis Sci (2004) 45: 708-13 [PMID:14744918] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
