N-homo-γ-linolenoylethanolamine [Ligand Id: 5444] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL121229 (Dihomo-Gamma-Linolenoyl Ethanolamide)
  • CB1 receptor/Cannabinoid CB1 receptor in Human [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
  • CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
ChEMBL Binding affinity against the cannabinoid receptor B 6.22 pKi 598 nM Ki J. Med. Chem. (1997) 40: 659-667 [PMID:9057852]
ChEMBL Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor] B 7.27 pKi 53.4 nM Ki J. Med. Chem. (2002) 45: 3649-3659 [PMID:12166938]
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL In vitro binding affinity was determined against rat brain Cannabinoid receptor 1 B 7.27 pKi 53.4 nM Ki J. Med. Chem. (1997) 40: 659-667 [PMID:9057852]
ChEMBL Binding affinity for cannabinoid receptor 1 B 7.28 pKi 53 nM Ki J. Med. Chem. (2005) 48: 5059-5087 [PMID:16078824]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]