N-homo-γ-linolenoylethanolamine [Ligand Id: 5444] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL121229 (Dihomo-Gamma-Linolenoyl Ethanolamide) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554] | ||||||||
| ChEMBL | Binding affinity against the cannabinoid receptor | B | 6.22 | pKi | 598 | nM | Ki | J Med Chem (1997) 40: 659-667 [PMID:9057852] |
| ChEMBL | Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor] | B | 7.27 | pKi | 53.4 | nM | Ki | J Med Chem (2002) 45: 3649-3659 [PMID:12166938] |
| CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] | ||||||||
| ChEMBL | In vitro binding affinity was determined against rat brain Cannabinoid receptor 1 | B | 7.27 | pKi | 53.4 | nM | Ki | J Med Chem (1997) 40: 659-667 [PMID:9057852] |
| ChEMBL | Binding affinity for cannabinoid receptor 1 | B | 7.28 | pKi | 53 | nM | Ki | J Med Chem (2005) 48: 5059-5087 [PMID:16078824] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
