azelastine   

GtoPdb Ligand ID: 7121

Synonyms: A-5610 | Astelin® | E-0659 | Rhinolast® | W-2979M
azelastine is an approved drug
Compound class: Synthetic organic
Comment: There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 38.13
Molecular weight 381.16
XLogP 4.95
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES CN1CCCC(CC1)n1nc(Cc2ccc(cc2)Cl)c2c(c1=O)cccc2
Isomeric SMILES CN1CCCC(CC1)n1nc(Cc2ccc(cc2)Cl)c2c(c1=O)cccc2
InChI InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3
InChI Key MBUVEWMHONZEQD-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one
International Nonproprietary Names
INN number INN
4074 azelastine
Synonyms
A-5610 | Astelin® | E-0659 | Rhinolast® | W-2979M
Comments
There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Database Links
CAS Registry No. 58581-89-8
ChEMBL Ligand CHEMBL639
DrugBank Ligand DB00972
DrugCentral Ligand 271
GtoPdb PubChem SID 178103698
PubChem CID 2267
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