Ligand id: 8251

Name: labetuzumab

Compound class Antibody
International Nonproprietary Names
INN number INN
8127 labetuzumab
Labetuzumab is a humanised mouse monoclonal antibody targeting CEACAM5 (CD66e), a tumour marker that can be measured in serum.
Labetuzumab can be labelled with radioactive isotopes such as yttrium-90 and iodine-131, providing targeted radioimmumotherapy.
Labetuzumab has been used to generate an antibody-drug conjugate (ADC) called labetuzumab govitecan, in which the antibody is covalently bound to SN-38, the active metabolite of the topoisomerase inhibitor, irinotecan.
Database Links
Specialist databases
IMGT/mAb-DB 62
Other databases
GtoPdb PubChem SID 249565931
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Wikipedia Labetuzumab