anandamide [Ligand Id: 2364] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL15848
  • Fatty acid amide hydrolase/Anandamide amidohydrolase in Human [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519]
  • Fatty acid amide hydrolase/Anandamide amidohydrolase in Rat [ChEMBL: CHEMBL3229] [GtoPdb: 1400] [UniProtKB: P97612]
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  • CB1 receptor/Cannabinoid CB1 receptor in Human [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
  • CB1 receptor/Cannabinoid CB1 receptor in Mouse [ChEMBL: CHEMBL3037] [GtoPdb: 56] [UniProtKB: P47746]
  • CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
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  • CB2 receptor/Cannabinoid CB2 receptor in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
  • CB2 receptor/Cannabinoid CB2 receptor in Mouse [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
  • CB2 receptor/Cannabinoid CB2 receptor in Rat [ChEMBL: CHEMBL2470] [GtoPdb: 57] [UniProtKB: Q9QZN9]
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  • TRPV2/Transient receptor potential cation channel subfamily V member 2 in Rat [ChEMBL: CHEMBL2863] [GtoPdb: 508] [UniProtKB: Q9WUD2]
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  • GPR18 in Human [GtoPdb: 89] [UniProtKB: Q14330]
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  • GPR55 in Human [GtoPdb: 109] [UniProtKB: Q9Y2T6]
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  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
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  • K2P3.1 in Human [GtoPdb: 515] [UniProtKB: O14649]
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  • Cav3.1 in Human [GtoPdb: 535] [UniProtKB: O43497]
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  • Cav3.2 in Human [GtoPdb: 536] [UniProtKB: O95180]
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  • Cav3.3 in Human [GtoPdb: 537] [UniProtKB: Q9P0X4]
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  • Kv1.2 in Human [GtoPdb: 539] [UniProtKB: P16389]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Fatty acid amide hydrolase/Anandamide amidohydrolase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519]
ChEMBL Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]AEA as substrate in the 0-25 uM conc B 5 pKi >10000 nM Ki J. Med. Chem. (2002) 45: 3709-3720 [PMID:12166944]
ChEMBL Inhibition of FAAH (unknown origin) B 5.39 pIC50 4100 nM IC50 J Med Chem (2018) 61: 5569-5579 [PMID:29856219]
ChEMBL Inhibition of FAAH B 5.47 pIC50 3400 nM IC50 J. Med. Chem. (2008) 51: 7327-7343 [PMID:18983142]
Fatty acid amide hydrolase/Anandamide amidohydrolase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3229] [GtoPdb: 1400] [UniProtKB: P97612]
ChEMBL Binding affinity towards Fatty-acid amide hydrolase (FAAH) in rat forebrain membranes B 5.52 pKi 3000 nM Ki Bioorg. Med. Chem. Lett. (2003) 13: 1977-1980 [PMID:12781177]
ChEMBL Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA B 4.93 pIC50 11748.98 nM IC50 J. Med. Chem. (2009) 52: 4613-4622 [PMID:19719235]
CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
ChEMBL Binding affinity towards cloned human Cannabinoid receptor 1 B 1.95 pKi 1.95 nM Log Ki J. Med. Chem. (2000) 43: 2300-2309 [PMID:10882356]
ChEMBL Ability to displace [3H]CP-55940 from the membranes prepared from HEK cell line with F3.25 (190)A mutant Cannabinoid receptor 1 B 5.74 pKi 1800 nM Ki J. Med. Chem. (2003) 46: 5139-5152 [PMID:14613317]
ChEMBL Ability to displace [3H]CP-55940 from the membranes prepared from HEK cell line with W5 43(280)A mutant Cannabinoid receptor 1 at 5 uM B 6.52 pKi 300 nM Ki J. Med. Chem. (2003) 46: 5139-5152 [PMID:14613317]
ChEMBL Ability to displace [3H]CP-55940 from the membranes prepared from HEK cell line with wild type Cannabinoid receptor 1 B 6.52 pKi 300 nM Ki J. Med. Chem. (2003) 46: 5139-5152 [PMID:14613317]
ChEMBL Ability to displace [3H]CP-55940 from the membranes prepared from HEK cell line with W6 48(357)A mutant in Cannabinoid receptor 1 B 6.52 pKi 300 nM Ki J. Med. Chem. (2003) 46: 5139-5152 [PMID:14613317]
ChEMBL Ability to displace [3H]CP-55940 from the membranes prepared from HEK cell line with F3.36 (201)A mutant Cannabinoid receptor 1 B 6.52 pKi 300 nM Ki J. Med. Chem. (2003) 46: 5139-5152 [PMID:14613317]
GtoPdb - - 7 pKi - - - Mol. Pharmacol. (1995) 48: 443-50 [PMID:7565624];
J. Pharmacol. Exp. Ther. (1996) 278: 989-99 [PMID:8819477]
ChEMBL Binding affinity to human CB1 receptor in presence of serine protease inhibitor PMSF B 7.05 pKi 89 nM Ki J. Med. Chem. (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL Displacement of [3H]CP-55940 from human CB1 receptor expressed in COS cells B 7.14 pKi 72 nM Ki J. Med. Chem. (2005) 48: 7343-7350 [PMID:16279794]
ChEMBL Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assay B 7.14 pKi 72 nM Ki J. Med. Chem. (2009) 52: 2506-2514 [PMID:19331413]
ChEMBL Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranes B 7.14 pKi 72 nM Ki Bioorg. Med. Chem. (2014) 22: 4770-4783 [PMID:25065940]
ChEMBL Displacement of [3H]CP-55940 from human recombinant CB1 receptor B 7.14 pKi 72 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 138-141 [PMID:16213718]
ChEMBL Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cells B 7.14 pKi 72 nM Ki Bioorg. Med. Chem. (2007) 15: 5406-5416 [PMID:17561406]
ChEMBL Displacement of [3H]CP-55-940 from human recombinant CB1 receptor in COS cells B 7.15 pKi 70 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 3765-3768 [PMID:16682198]
ChEMBL Binding affinity to human recombinant CB1 receptor expressed in COS cells B 7.15 pKi 70 nM Ki J. Med. Chem. (2006) 49: 2333-2338 [PMID:16570929]
ChEMBL Displacement of [3H]CP-55-940 from human recombinant CB1 receptor expressed in COS cells B 7.15 pKi 70 nM Ki J. Med. Chem. (2009) 52: 1005-1017 [PMID:19161308]
ChEMBL Displacement of [3H]CP55940 from human CB1 receptor expressed in human HEK293 cells in presence of 100 nM PMSF B 7.15 pKi 70 nM Ki J. Med. Chem. (2011) 54: 8278-8288 [PMID:22044209]
ChEMBL Binding affinity to CB1R (unknown origin) B 7.3 pKi 50 nM Ki J Med Chem (2017) 60: 4-46 [PMID:27766867]
ChEMBL Binding affinity for human cannabinoid receptor 1 B 7.3 pKi 50 nM Ki J. Med. Chem. (2005) 48: 5059-5087 [PMID:16078824]
ChEMBL Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor] B 7.41 pKi 39.2 nM Ki J. Med. Chem. (2002) 45: 3649-3659 [PMID:12166938]
ChEMBL Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cell membrane B 7.96 pKi 11 nM Ki J. Med. Chem. (2009) 52: 3001-3009 [PMID:19361197]
CB1 receptor/Cannabinoid CB1 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3037] [GtoPdb: 56] [UniProtKB: P47746]
ChEMBL Binding affinity for Cannabinoid receptor 1 in absence of phenylmethylsulfonyl fluoride (PMSF) B 5.27 pKi 5400 nM Ki J. Med. Chem. (1997) 40: 3617-3625 [PMID:9357528]
ChEMBL Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF) B 7.05 pKi 89 nM Ki J. Med. Chem. (1997) 40: 3617-3625 [PMID:9357528]
ChEMBL Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain membrane B 4.92 pIC50 12000 nM IC50 Bioorg. Med. Chem. Lett. (2003) 13: 3301-3303 [PMID:12951114]
ChEMBL Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain membrane in the presence of PMSF B 7.41 pIC50 39 nM IC50 Bioorg. Med. Chem. Lett. (2003) 13: 3301-3303 [PMID:12951114]
ChEMBL Agonist activity at CB1 receptor expressed in mouse brain membrane by [35S]GTPgammaS binding assay F 6.44 pEC50 360 nM EC50 J. Med. Chem. (2009) 52: 3001-3009 [PMID:19361197]
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the absence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]CP-55940 as radioligand B 5.24 pKi 5810 nM Ki J. Med. Chem. (1998) 41: 5353-5361 [PMID:9876105]
ChEMBL The compound was tested for Ki value against rat whole brain P2 membrane preparation in absence of enzyme inhibitor PMSF B 5.27 pKi 5400 nM Ki J. Med. Chem. (1999) 42: 1975-1981 [PMID:10354405]
ChEMBL Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes in absence of FAAH inhibitor PMSF by radioligand binding assay B 6 pKi >1000 nM Ki J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
ChEMBL Concentration required to displace 0.4 nM [3H]SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulfonyl fluoride B 6.1 pKi 800 nM Ki Bioorg. Med. Chem. Lett. (2001) 11: 447-449 [PMID:11229744]
ChEMBL Displacement of [3H]SR141716A from CB1 receptor in CD rat brain membranes B 6.4 pKi 400 nM Ki J. Nat. Prod. (2003) 66: 1364-1368 [PMID:14575438]
ChEMBL Binding affinity to CB1 cannabinoid receptor using [3H]WIN-55212-2 in rat cerebellum membranes B 6.55 pKi 285 nM Ki J. Med. Chem. (2001) 44: 4505-4508 [PMID:11741470]
ChEMBL Displacement of [3H]SR141716A from CB1 receptor in rat cerebellar membrane after 90 mins by scintillation counting B 6.88 pKi 132 nM Ki Eur. J. Med. Chem. (2009) 44: 4889-4895 [PMID:19762126]
ChEMBL Displacement of [3H]CP-55940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSF B 7.05 pKi 90 nM Ki J. Med. Chem. (2002) 45: 3709-3720 [PMID:12166944]
ChEMBL Binding affinity towards Cannabinoid receptor 1 in rat forebrain membranes using [3H]CP-55940 as radioligand B 7.05 pKi 90 nM Ki Bioorg. Med. Chem. Lett. (2003) 13: 1977-1980 [PMID:12781177]
ChEMBL The compound was tested for Ki value against rat whole brain P2 membrane preparation in presence of enzyme inhibitor PMSF. B 7.05 pKi 89 nM Ki J. Med. Chem. (1999) 42: 1975-1981 [PMID:10354405]
ChEMBL Displacement of [3H]CP55940 from CB1 receptor in Wistar rat brain incubated for 60 mins by radioactive filter binding assay B 7.05 pKi 89 nM Ki Eur. J. Med. Chem. (2016) 112: 66-80 [PMID:26890113]
ChEMBL Displacement of [3H]CP-55940 from Cannabinoid receptor 1 of rat forebrain membranes B 7.11 pKi 78 nM Ki J. Med. Chem. (1996) 39: 4515-4519 [PMID:8893848]
ChEMBL Tested for binding affinity to Cannabinoid receptor 1 B 7.11 pKi 78 nM Ki J. Med. Chem. (1999) 42: 896-902 [PMID:10072686]
ChEMBL Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes in presence of FAAH inhibitor PMSF by radioligand binding assay B 7.13 pKi 74 nM Ki J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
ChEMBL Binding affinity for cannabinoid receptor 1 B 7.14 pKi 72 nM Ki J. Med. Chem. (2005) 48: 5059-5087 [PMID:16078824]
ChEMBL Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]CP-55940 as radioligand B 7.21 pKi 61 nM Ki J. Med. Chem. (1998) 41: 5353-5361 [PMID:9876105]
ChEMBL In vitro binding affinity was determined against rat brain Cannabinoid receptor 1 B 7.41 pKi 39.2 nM Ki J. Med. Chem. (1997) 40: 659-667 [PMID:9057852]
ChEMBL Displacement of [3H]CP-55940 binding to Cannabinoid receptor 1 in rat brain membranes B 7.66 pKi 22 nM Ki J. Med. Chem. (1998) 41: 4207-4215 [PMID:9784095]
ChEMBL Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with rat brain membrane in the presence of PMSF B 7.4 pIC50 40 nM IC50 Bioorg. Med. Chem. Lett. (2003) 13: 3301-3303 [PMID:12951114]
ChEMBL Cannabinoid receptor 1 dependent activity of compound was evaluated by using [35S]GTP-gamma-S-binding studies F 4.8 pEC50 15848.93 nM EC50 Bioorg. Med. Chem. Lett. (2004) 14: 3231-3234 [PMID:15149681]
ChEMBL Displacement of [35S]GTP-gamma-S from rat cerebellar CB1 receptor F 4.8 pEC50 15848.93 nM EC50 J. Med. Chem. (2006) 49: 554-566 [PMID:16420041]
ChEMBL Agonist activity at rat CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins F 7.16 pEC50 69 nM EC50 J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL Binding affinity towards cloned human cannabinoid receptor 2 B 2.57 pKi 2.57 nM Log Ki J. Med. Chem. (2000) 43: 2300-2309 [PMID:10882356]
ChEMBL Binding affinity to human CB2 cannabinoid receptor using [3H]CP-55940 in HEK293 EBNA transfected cells B 6 pKi >1000 nM Ki J. Med. Chem. (2001) 44: 4505-4508 [PMID:11741470]
GtoPdb - - 6.4 pKi - - - Mol. Pharmacol. (1995) 48: 443-50 [PMID:7565624];
J. Pharmacol. Exp. Ther. (1996) 278: 989-99 [PMID:8819477];
Biochem. Pharmacol. (1995) 50: 83-90 [PMID:7605349]
ChEMBL Binding affinity to human CB2 receptor in presence of serine protease inhibitor PMSF B 6.43 pKi 371 nM Ki J. Med. Chem. (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL Binding affinity to human recombinant CB2 receptor expressed in COS cells B 6.74 pKi 180 nM Ki J. Med. Chem. (2006) 49: 2333-2338 [PMID:16570929]
ChEMBL Displacement of [3H]CP-55-940 from human recombinant CB2 receptor in COS cells B 6.74 pKi 180 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 3765-3768 [PMID:16682198]
ChEMBL Displacement of [3H]CP-55-940 from human recombinant CB2 receptor expressed in COS cells B 6.74 pKi 180 nM Ki J. Med. Chem. (2009) 52: 1005-1017 [PMID:19161308]
ChEMBL Displacement of [3H]CP-55940 from human recombinant CB2 receptor B 6.74 pKi 180 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 138-141 [PMID:16213718]
ChEMBL Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cell membrane B 6.77 pKi 168 nM Ki J. Med. Chem. (2009) 52: 3001-3009 [PMID:19361197]
ChEMBL Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cell membranes in absence of FAAH inhibitor PMSF by radioligand binding assay B 6.8 pKi 160 nM Ki J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
CB2 receptor/Cannabinoid CB2 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
ChEMBL Binding affinity towards Cannabinoid receptor 2 from mouse spleen membranes using 0.8 nM [3H]CP-55940 as radioligand B 5.71 pKi 1930 nM Ki J. Med. Chem. (1998) 41: 5353-5361 [PMID:9876105]
ChEMBL Compound was evaluated for its binding affinity for mouse spleen Cannabinoid receptor 2 B 5.72 pKi 1926 nM Ki J. Med. Chem. (1996) 39: 4515-4519 [PMID:8893848]
ChEMBL Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cell membranes in absence of FAAH inhibitor PMSF by radioligand binding assay B 6 pKi >1000 nM Ki J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
CB2 receptor/Cannabinoid CB2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2470] [GtoPdb: 57] [UniProtKB: Q9QZN9]
ChEMBL Displacement of [3H]CP-55940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSF B 6.44 pKi 360 nM Ki J. Med. Chem. (2002) 45: 3709-3720 [PMID:12166944]
Potassium channel subfamily K member 2 in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075183] [UniProtKB: Q8HY88]
ChEMBL Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currents B 6 pIC50 1000 nM IC50 J. Med. Chem. (2016) 59: 5149-5157 [PMID:26588045]
TRPV2/Transient receptor potential cation channel subfamily V member 2 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2863] [GtoPdb: 508] [UniProtKB: Q9WUD2]
ChEMBL Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry B 5.07 pIC50 8600 nM IC50 J Med Chem (2018) 61: 8255-8281 [PMID:30176215]
ChEMBL Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry B 6.02 pIC50 960 nM IC50 J Med Chem (2018) 61: 8255-8281 [PMID:30176215]
TRPV1/Vanilloid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4794] [GtoPdb: 507] [UniProtKB: Q8NER1]
GtoPdb - - 5 pEC50 - - - J. Biol. Chem. (2003) 278: 30429-34 [PMID:12761211]
GtoPdb - - 5.9 pEC50 - - - Br. J. Pharmacol. (2000) 129: 227-30 [PMID:10694225]
ChEMBL Activation of human VR1 expressed in HEK293 cells assessed as stimulation of Ca2+ influx B 6.2 pEC50 630 nM EC50 J. Med. Chem. (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL Agonist activity on human recombinant TRPV1-mediated enhancement of intracellular calcium concentration in HEK293 cells F 6.31 pEC50 490 nM EC50 J. Med. Chem. (2006) 49: 2333-2338 [PMID:16570929]
ChEMBL Agonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level F 6.7 pEC50 200 nM EC50 J. Med. Chem. (2009) 52: 3001-3009 [PMID:19361197]
ChEMBL Agonist activity at TRPV1 receptor (unknown origin) B 7.8 pEC50 15.8 nM EC50 J. Med. Chem. (2013) 56: 1811-1829 [PMID:23384387]
TRPV1/Vanilloid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5102] [GtoPdb: 507] [UniProtKB: O35433]
ChEMBL Binding affinity to vanilloid VR1 receptor using [3H]resiniferatoxin ([3H]-RTX) in rat spinal cord membranes B 6.77 pKi 169 nM Ki J. Med. Chem. (2001) 44: 4505-4508 [PMID:11741470]
GtoPdb - - 5.3 pEC50 - - - Nature (1999) 400: 452-7 [PMID:10440374]
GPR18 in Human [GtoPdb: 89] [UniProtKB: Q14330]
GtoPdb - - 5.42 pEC50 3830 nM EC50 Br. J. Pharmacol. (2012) 165: 2414-24 [PMID:21595653]
GPR55 in Human [GtoPdb: 109] [UniProtKB: Q9Y2T6]
GtoPdb - - 7.74 pEC50 18 nM EC50 Br. J. Pharmacol. (2007) 152: 1092-101 [PMID:17876302]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 7.4 pEC50 38 nM EC50
K2P3.1 in Human [GtoPdb: 515] [UniProtKB: O14649]
GtoPdb - - 5.6 pIC50 2700 nM IC50 EMBO J. (2001) 20: 47-54 [PMID:11226154]
GtoPdb - - 6.15 pIC50 ~700 nM IC50 EMBO J. (2001) 20: 47-54 [PMID:11226154]
Cav3.1 in Human [GtoPdb: 535] [UniProtKB: O43497]
GtoPdb - - 5.4 pIC50 - - - EMBO J. (2001) 20: 7033-40 [PMID:11742980]
Cav3.2 in Human [GtoPdb: 536] [UniProtKB: O95180]
GtoPdb - - 6.5 pIC50 - - - EMBO J. (2001) 20: 7033-40 [PMID:11742980]
Cav3.3 in Human [GtoPdb: 537] [UniProtKB: Q9P0X4]
GtoPdb - - 6 pIC50 - - - EMBO J. (2001) 20: 7033-40 [PMID:11742980]
Kv1.2 in Human [GtoPdb: 539] [UniProtKB: P16389]
GtoPdb - - 5.6 pIC50 2700 nM IC50 Neuropharmacology (1996) 35: 983-91 [PMID:8938728]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]