compound 5 [Noble et al., 1992] [Ligand Id: 8844] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1161242
  • INPP5A/Type I inositol-1,4,5-trisphosphate 5-phosphatase in Human [ChEMBL: CHEMBL4243] [GtoPdb: 1453] [UniProtKB: Q14642]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
INPP5A/Type I inositol-1,4,5-trisphosphate 5-phosphatase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4243] [GtoPdb: 1453] [UniProtKB: Q14642]
ChEMBL The compound was evaluated for inhibition of Inositol-1,4,5-trisphosphate 5-phosphatase B 5.89 pKi 1300 nM Ki Bioorg. Med. Chem. Lett. (1992) 2: 471-476
GtoPdb Using 5-phosphatase from human erythrocyte membranes. - 5.89 pKi 1300 nM Ki Bioorg Med Chem Lett (1992) 2: 471-476

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]