JNJ-67569762 [Ligand Id: 11751] activity data from GtoPdb

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  • beta-secretase 1 in Human [GtoPdb: 2330] [UniProtKB: P56817]
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  • beta-secretase 2 in Human [GtoPdb: 2331] [UniProtKB: Q9Y5Z0]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
beta-secretase 1 in Human [GtoPdb: 2330] [UniProtKB: P56817]
GtoPdb - - 8.57 pIC50 2.7 nM IC50 J Med Chem (2021) 64: 14175-14191 [PMID:34553934]
beta-secretase 2 in Human [GtoPdb: 2331] [UniProtKB: Q9Y5Z0]
GtoPdb - - 6.71 pIC50 195 nM IC50 J Med Chem (2021) 64: 14175-14191 [PMID:34553934]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.