ChEMBL ligand: CHEMBL1215923 (Bimosiamose, TBC-1269)
selectin P (CD62)/P-selectin in Human [ChEMBL: CHEMBL5378] [GtoPdb: 3103] [UniProtKB: P16109] There should be some charts here, you may need to enable JavaScript!
P-selectin glycoprotein ligand 1 in Human [ChEMBL: CHEMBL4183] [UniProtKB: Q14242] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
selectin P (CD62)/P-selectin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5378] [GtoPdb: 3103] [UniProtKB: P16109]
ChEMBL	Inhibition of human P-selectin after 2 hrs	B	4.02	pIC50	95000	nM	IC50	J Med Chem (2007) 50: 1101-1115 [PMID:17302397]
GtoPdb	Inhibition of P-selectin binding in an HL-60 cellular assay.	-	4.15	pIC50	70000	nM	IC50	J Med Chem (1998) 41: 1099-111 [PMID:9544210]
ChEMBL	Inhibition of P-selectin in human HL-60 cells	B	4.15	pIC50	70000	nM	IC50	J Med Chem (2010) 53: 6003-6017 [PMID:20718494]
P-selectin glycoprotein ligand 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4183] [UniProtKB: Q14242]
ChEMBL	Inhibition of P-selectin-mediated adhesion of HL60 cells	B	4.15	pIC50	70000	nM	IC50	J Med Chem (2007) 50: 21-39 [PMID:17201408]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]