ChEMBL ligand: CHEMBL3108800
bromodomain containing 4/Bromodomain-containing protein 4 in Human [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885] There should be some charts here, you may need to enable JavaScript!
bromodomain containing 9/Bromodomain-containing protein 9 in Human [ChEMBL: CHEMBL3108640] [GtoPdb: 2728] [UniProtKB: Q9H8M2] There should be some charts here, you may need to enable JavaScript!
CECR2 histone acetyl-lysine reader/Cat eye syndrome critical region protein 2 in Human [ChEMBL: CHEMBL3108639] [GtoPdb: 2733] [UniProtKB: Q9BXF3] There should be some charts here, you may need to enable JavaScript!
CREB binding protein/CREB-binding protein in Human [ChEMBL: CHEMBL5747] [GtoPdb: 2734] [UniProtKB: Q92793] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
bromodomain containing 4/Bromodomain-containing protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885]
ChEMBL	Displacement of H4Ac4 peptide from BRD4 bromodomain-1 (unknown origin) by AlphaScreen assay	B	6.6	pIC50	251.19	nM	IC50	J Med Chem (2014) 57: 462-476 [PMID:24313754]
bromodomain containing 9/Bromodomain-containing protein 9 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3108640] [GtoPdb: 2728] [UniProtKB: Q9H8M2]
ChEMBL	Displacement of H2K9(Ac)K13(Ac)K15(Ac) peptide from BRD9 bromodomain (unknown origin) by AlphaScreen assay	B	6.5	pIC50	316.23	nM	IC50	J Med Chem (2014) 57: 462-476 [PMID:24313754]
GtoPdb	-	-	6.5	pIC50	316	nM	IC50	J Med Chem (2014) 57: 462-76 [PMID:24313754]
CECR2 histone acetyl-lysine reader/Cat eye syndrome critical region protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3108639] [GtoPdb: 2733] [UniProtKB: Q9BXF3]
ChEMBL	Displacement of H4Ac4 peptide from CECR2 bromodomain (unknown origin) by AlphaScreen assay	B	6.8	pIC50	158.49	nM	IC50	J Med Chem (2014) 57: 462-476 [PMID:24313754]
GtoPdb	-	-	6.8	pIC50	158	nM	IC50	J Med Chem (2014) 57: 462-76 [PMID:24313754]
CREB binding protein/CREB-binding protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5747] [GtoPdb: 2734] [UniProtKB: Q92793]
ChEMBL	Displacement of H3K56(Ac) peptide from CREBBP bromodomain (unknown origin) by AlphaScreen assay	B	6.2	pIC50	630.96	nM	IC50	J Med Chem (2014) 57: 462-476 [PMID:24313754]
GtoPdb	-	-	6.2	pIC50	631	nM	IC50	J Med Chem (2014) 57: 462-76 [PMID:24313754]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]