lintitript [Ligand Id: 890] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL249973 (Lintitript, SR-27897) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CCK1 receptor/Cholecystokinin A receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238] | ||||||||
| GtoPdb | - | - | 8.3 | pIC50 | 5 | nM | IC50 | Eur J Pharmacol (2000) 400: 185-94 [PMID:10988332] |
| ChEMBL | Binding affinity to human CCK1 receptor | B | 9.25 | pIC50 | 0.56 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 6493-6498 [PMID:17933530] |
| CCK1 receptor in Rat [GtoPdb: 76] [UniProtKB: P30551] | ||||||||
| GtoPdb | - | - | 9.7 | pIC50 | - | - | - | Eur J Pharmacol (1993) 232: 13-9 [PMID:7681406] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
