AZD7545 [Ligand Id: 9362] activity data from GtoPdb

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  • pyruvate dehydrogenase kinase 2 in Human [GtoPdb: 2142] [UniProtKB: Q15119]
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  • pyruvate dehydrogenase kinase 1 in Human [GtoPdb: 2915] [UniProtKB: Q15118]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
pyruvate dehydrogenase kinase 2 in Human [GtoPdb: 2142] [UniProtKB: Q15119]
GtoPdb In a biochemical enzyme assay - 8.19 pIC50 6.4 nM IC50 Biochem Soc Trans (2003) 31: 1168-70 [PMID:14641019]
pyruvate dehydrogenase kinase 1 in Human [GtoPdb: 2915] [UniProtKB: Q15118]
GtoPdb In a biochemical enzyme assay - 7.43 pIC50 36.8 nM IC50 Biochem Soc Trans (2003) 31: 1168-70 [PMID:14641019]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.