moxisylyte   Click here for help

GtoPdb Ligand ID: 12306

Synonyms: Opilon® | thymoxamine
Approved drug
moxisylyte is an approved drug
Compound class: Synthetic organic
Comment: Moxisylyte is an antagonist of α1 adrenoceptors, with some selectivity for the α1A subtype [2]. It improves blood circulation to the extremities and has been used to treat primary Raynaud's syndrome .
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 38.77
Molecular weight 279.18
XLogP 2.99
No. Lipinski's rules broken 0
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Canonical SMILES CN(CCOc1cc(C)c(cc1C(C)C)OC(=O)C)C
Isomeric SMILES Cc1cc(c(cc1OC(=O)C)C(C)C)OCCN(C)C
InChI InChI=1S/C16H25NO3/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6/h9-11H,7-8H2,1-6H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
International Nonproprietary Names Click here for help
INN number INN
1538 moxisylyte
Synonyms Click here for help
Opilon® | thymoxamine
Database Links Click here for help
GtoPdb PubChem SID 479821097
PubChem CID 4260
Search Google for chemical match using the InChIKey VRYMTAVOXVTQEF-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey VRYMTAVOXVTQEF-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey VRYMTAVOXVTQEF-UHFFFAOYSA-N