chlorpromazine [Ligand Id: 83] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL71 (Sonazine, NSC-167745, J2.794D, Elmarin, SKF-2601A, NSC-226514, Chlorpromazine tannate, Chlorpromazine, Largactil, Chlorpromazine phenolphthalinate, Chlorpromazine hibenzate, Megaphen, Thorazine)
  • Acetylcholine receptor protein alpha chain in Torpedo californica [ChEMBL: CHEMBL3097] [UniProtKB: P02710]
  • This target only has 0 pki data point
  • 0
1 CHEMBL71_lig_chart_1 Acetylcholine receptor protein alpha chain Torpedo californica
There should be some charts here, you may need to enable JavaScript!
  • α1A-adrenoceptor/Alpha-1a adrenergic receptor in Rat [ChEMBL: CHEMBL319] [GtoPdb: 22] [UniProtKB: P43140]
  • This target only has 1 pki data point
  • 8.46
2 CHEMBL71_lig_chart_2 Alpha-1a adrenergic receptor Rat
There should be some charts here, you may need to enable JavaScript!
  • α1B-adrenoceptor/Alpha-1b adrenergic receptor in Rat [ChEMBL: CHEMBL315] [GtoPdb: 23] [UniProtKB: P15823]
  • This target only has 1 pki data point
  • 8.3
3 CHEMBL71_lig_chart_3 Alpha-1b adrenergic receptor Rat
There should be some charts here, you may need to enable JavaScript!
  • α1D-adrenoceptor/Alpha-1d adrenergic receptor in Human [ChEMBL: CHEMBL223] [GtoPdb: 24] [UniProtKB: P25100]
  • This target only has 1 pki data point
  • 8.71
4 CHEMBL71_lig_chart_4 Alpha-1d adrenergic receptor Human
There should be some charts here, you may need to enable JavaScript!
  • α2A-adrenoceptor/Alpha-2a adrenergic receptor in Human [ChEMBL: CHEMBL1867] [GtoPdb: 25] [UniProtKB: P08913]
  • 6.74
5 CHEMBL71_lig_chart_5 Alpha-2a adrenergic receptor Human
There should be some charts here, you may need to enable JavaScript!
  • α2B-adrenoceptor/Alpha-2b adrenergic receptor in Human [ChEMBL: CHEMBL1942] [GtoPdb: 26] [UniProtKB: P18089]
  • 8.11
6 CHEMBL71_lig_chart_6 Alpha-2b adrenergic receptor Human
There should be some charts here, you may need to enable JavaScript!
  • α2C-adrenoceptor/Alpha-2c adrenergic receptor in Human [ChEMBL: CHEMBL1916] [GtoPdb: 27] [UniProtKB: P18825]
  • 7.33
7 CHEMBL71_lig_chart_7 Alpha-2c adrenergic receptor Human
There should be some charts here, you may need to enable JavaScript!
  • Arachidonate 15-lipoxygenase in Rabbit [ChEMBL: CHEMBL4358] [UniProtKB: P12530]
  • This target only has 0 pki data point
  • 0
8 CHEMBL71_lig_chart_8 Arachidonate 15-lipoxygenase Rabbit
There should be some charts here, you may need to enable JavaScript!
  • ABCB11/Bile salt export pump in Human [ChEMBL: CHEMBL6020] [GtoPdb: 778] [UniProtKB: O95342]
  • This target only has 0 pki data point
  • 0
9 CHEMBL71_lig_chart_9 Bile salt export pump Human
There should be some charts here, you may need to enable JavaScript!
  • Calmodulin in Human [ChEMBL: CHEMBL6093] [UniProtKB: P0DP23]
  • Calmodulin in Bovine [ChEMBL: CHEMBL6092] [UniProtKB: P62157]
  • This target only has 1 pki data point
  • 0
10 CHEMBL71_lig_chart_10 Calmodulin HumanBovine
There should be some charts here, you may need to enable JavaScript!
  • δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
  • This target only has 1 pki data point
  • 5.13
11 CHEMBL71_lig_chart_11 Delta opioid receptor Human
There should be some charts here, you may need to enable JavaScript!
  • D1 receptor/Dopamine D1 receptor in Human [ChEMBL: CHEMBL2056] [GtoPdb: 214] [UniProtKB: P21728]
  • D1 receptor/Dopamine D1 receptor in Rat [ChEMBL: CHEMBL265] [GtoPdb: 214] [UniProtKB: P18901]
  • 7.45
12 CHEMBL71_lig_chart_12 Dopamine D1 receptor HumanRat
There should be some charts here, you may need to enable JavaScript!
  • D2 receptor/Dopamine D2 receptor in Human [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
  • Dopamine D2 receptor in Bovine [ChEMBL: CHEMBL3998] [UniProtKB: P20288]
  • D2 receptor/Dopamine D2 receptor in Rat [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169]
  • 8.52
13 CHEMBL71_lig_chart_13 Dopamine D2 receptor HumanBovineRat
There should be some charts here, you may need to enable JavaScript!
  • D3 receptor/Dopamine D3 receptor in Human [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462]
  • D3 receptor in Rat [GtoPdb: 216] [UniProtKB: P19020]
  • 7.2
14 CHEMBL71_lig_chart_14 Dopamine D3 receptor HumanRat
There should be some charts here, you may need to enable JavaScript!
  • D4 receptor/Dopamine D4 receptor in Human [ChEMBL: CHEMBL219] [GtoPdb: 217] [UniProtKB: P21917]
  • 7.52
15 CHEMBL71_lig_chart_15 Dopamine D4 receptor Human
There should be some charts here, you may need to enable JavaScript!
  • D5 receptor/Dopamine D5 receptor in Human [ChEMBL: CHEMBL1850] [GtoPdb: 218] [UniProtKB: P21918]
  • 6.83
16 CHEMBL71_lig_chart_16 Dopamine D5 receptor Human
There should be some charts here, you may need to enable JavaScript!
  • DAT/Dopamine transporter in Human [ChEMBL: CHEMBL238] [GtoPdb: 927] [UniProtKB: Q01959]
  • This target only has 1 pki data point
  • 5.68
17 CHEMBL71_lig_chart_17 Dopamine transporter Human
There should be some charts here, you may need to enable JavaScript!
  • epidermal growth factor receptor/Epidermal growth factor receptor erbB1 in Human [ChEMBL: CHEMBL203] [GtoPdb: 1797] [UniProtKB: P00533]
  • This target only has 0 pki data point
  • 0
18 CHEMBL71_lig_chart_18 Epidermal growth factor receptor erbB1 Human
There should be some charts here, you may need to enable JavaScript!
19 CHEMBL71_lig_chart_19 Glutamate [NMDA] receptor Human
There should be some charts here, you may need to enable JavaScript!
20 CHEMBL71_lig_chart_20 Glutamate NMDA receptor Rat
There should be some charts here, you may need to enable JavaScript!
  • Kv11.1/HERG in Human [ChEMBL: CHEMBL240] [GtoPdb: 572] [UniProtKB: Q12809]
  • This target only has 1 pki data point
  • 5.32
21 CHEMBL71_lig_chart_21 HERG Human
There should be some charts here, you may need to enable JavaScript!
  • H1 receptor/Histamine H1 receptor in Human [ChEMBL: CHEMBL231] [GtoPdb: 262] [UniProtKB: P35367]
  • Histamine H1 receptor in Guinea pig [ChEMBL: CHEMBL3943] [UniProtKB: P31389]
  • 7.3
22 CHEMBL71_lig_chart_22 Histamine H1 receptor HumanGuinea pig
There should be some charts here, you may need to enable JavaScript!
  • H2 receptor/Histamine H2 receptor in Human [ChEMBL: CHEMBL1941] [GtoPdb: 263] [UniProtKB: P25021]
  • This target only has 1 pki data point
  • 5.59
23 CHEMBL71_lig_chart_23 Histamine H2 receptor Human
There should be some charts here, you may need to enable JavaScript!
  • H3 receptor/Histamine H3 receptor in Human [ChEMBL: CHEMBL264] [GtoPdb: 264] [UniProtKB: Q9Y5N1]
  • This target only has 1 pki data point
  • 6
24 CHEMBL71_lig_chart_24 Histamine H3 receptor Human
There should be some charts here, you may need to enable JavaScript!
  • κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
  • This target only has 1 pki data point
  • 5.35
25 CHEMBL71_lig_chart_25 Kappa opioid receptor Human
There should be some charts here, you may need to enable JavaScript!
  • MC3 receptor/Melanocortin receptor 3 in Human [ChEMBL: CHEMBL4644] [GtoPdb: 284] [UniProtKB: P41968]
  • This target only has 1 pki data point
  • 4.67
26 CHEMBL71_lig_chart_26 Melanocortin receptor 3 Human
There should be some charts here, you may need to enable JavaScript!
  • MC4 receptor/Melanocortin receptor 4 in Human [ChEMBL: CHEMBL259] [GtoPdb: 285] [UniProtKB: P32245]
  • This target only has 1 pki data point
  • 4.84
27 CHEMBL71_lig_chart_27 Melanocortin receptor 4 Human
There should be some charts here, you may need to enable JavaScript!
  • MC5 receptor/Melanocortin receptor 5 in Human [ChEMBL: CHEMBL4608] [GtoPdb: 286] [UniProtKB: P33032]
  • This target only has 1 pki data point
  • 5.15
28 CHEMBL71_lig_chart_28 Melanocortin receptor 5 Human
There should be some charts here, you may need to enable JavaScript!
  • μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
  • This target only has 1 pki data point
  • 5.23
29 CHEMBL71_lig_chart_29 Mu opioid receptor Human
There should be some charts here, you may need to enable JavaScript!
  • M1 receptor/Muscarinic acetylcholine receptor M1 in Human [ChEMBL: CHEMBL216] [GtoPdb: 13] [UniProtKB: P11229]
  • 7.3
30 CHEMBL71_lig_chart_30 Muscarinic acetylcholine receptor M1 Human
There should be some charts here, you may need to enable JavaScript!
  • M2 receptor/Muscarinic acetylcholine receptor M2 in Human [ChEMBL: CHEMBL211] [GtoPdb: 14] [UniProtKB: P08172]
  • This target only has 1 pki data point
  • 6.63
31 CHEMBL71_lig_chart_31 Muscarinic acetylcholine receptor M2 Human
There should be some charts here, you may need to enable JavaScript!
  • M3 receptor/Muscarinic acetylcholine receptor M3 in Human [ChEMBL: CHEMBL245] [GtoPdb: 15] [UniProtKB: P20309]
  • This target only has 1 pki data point
  • 7.36
32 CHEMBL71_lig_chart_32 Muscarinic acetylcholine receptor M3 Human
There should be some charts here, you may need to enable JavaScript!
  • M4 receptor/Muscarinic acetylcholine receptor M4 in Human [ChEMBL: CHEMBL1821] [GtoPdb: 16] [UniProtKB: P08173]
  • 7.24
33 CHEMBL71_lig_chart_33 Muscarinic acetylcholine receptor M4 Human
There should be some charts here, you may need to enable JavaScript!
  • M5 receptor/Muscarinic acetylcholine receptor M5 in Human [ChEMBL: CHEMBL2035] [GtoPdb: 17] [UniProtKB: P08912]
  • This target only has 1 pki data point
  • 7.74
34 CHEMBL71_lig_chart_34 Muscarinic acetylcholine receptor M5 Human
There should be some charts here, you may need to enable JavaScript!
  • NK2 receptor/Neurokinin 2 receptor in Human [ChEMBL: CHEMBL2327] [GtoPdb: 361] [UniProtKB: P21452]
  • This target only has 1 pki data point
  • 5.04
35 CHEMBL71_lig_chart_35 Neurokinin 2 receptor Human
There should be some charts here, you may need to enable JavaScript!
  • NET/Norepinephrine transporter in Human [ChEMBL: CHEMBL222] [GtoPdb: 926] [UniProtKB: P23975]
  • This target only has 1 pki data point
  • 7.72
36 CHEMBL71_lig_chart_36 Norepinephrine transporter Human
There should be some charts here, you may need to enable JavaScript!
37 CHEMBL71_lig_chart_37 P-glycoprotein 1 Human
There should be some charts here, you may need to enable JavaScript!
  • Plasmodium falciparum [ChEMBL: CHEMBL364]
  • This target only has 0 pki data point
  • 0
38 CHEMBL71_lig_chart_38 Plasmodium falciparum Plasmodium falciparum
There should be some charts here, you may need to enable JavaScript!
  • Pleiotropic ABC efflux transporter of multiple drugs in Saccharomyces cerevisiae S288c [ChEMBL: CHEMBL1697658] [UniProtKB: P33302]
  • This target only has 0 pki data point
  • 0
39 CHEMBL71_lig_chart_39 Pleiotropic ABC efflux transporter of multiple drugs Saccharomyces cerevisiae S288c
There should be some charts here, you may need to enable JavaScript!
  • K2P2.1/Potassium channel subfamily K member 2 in Human [ChEMBL: CHEMBL2321615] [GtoPdb: 514] [UniProtKB: O95069]
  • This target only has 0 pki data point
  • 0
40 CHEMBL71_lig_chart_40 Potassium channel subfamily K member 2 Human
There should be some charts here, you may need to enable JavaScript!
  • Prion protein in Human [ChEMBL: CHEMBL4869] [UniProtKB: P04156]
  • Prion protein in Mouse [ChEMBL: CHEMBL3698] [UniProtKB: P04925]
  • This target only has 0 pki data point
  • 0
41 CHEMBL71_lig_chart_41 Prion protein HumanMouse
There should be some charts here, you may need to enable JavaScript!
  • erb-b2 receptor tyrosine kinase 2/Receptor protein-tyrosine kinase erbB-2 in Human [ChEMBL: CHEMBL1824] [GtoPdb: 2019] [UniProtKB: P04626]
  • This target only has 0 pki data point
  • 0
42 CHEMBL71_lig_chart_42 Receptor protein-tyrosine kinase erbB-2 Human
There should be some charts here, you may need to enable JavaScript!
  • Sarcoplasmic/endoplasmic reticulum calcium ATP-ase in Rabbit [ChEMBL: CHEMBL4693] [UniProtKB: P04191]
  • This target only has 0 pki data point
  • 0
43 CHEMBL71_lig_chart_43 Sarcoplasmic/endoplasmic reticulum calcium ATP-ase Rabbit
There should be some charts here, you may need to enable JavaScript!
  • 5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908]
  • 5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Rat [ChEMBL: CHEMBL273] [GtoPdb: 1] [UniProtKB: P19327]
  • 6.16
44 CHEMBL71_lig_chart_44 Serotonin 1a (5-HT1a) receptor HumanRat
There should be some charts here, you may need to enable JavaScript!
  • 5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Rat [ChEMBL: CHEMBL3459] [GtoPdb: 2] [UniProtKB: P28564]
  • This target only has 1 pki data point
  • 5.74
45 CHEMBL71_lig_chart_45 Serotonin 1b (5-HT1b) receptor Rat
There should be some charts here, you may need to enable JavaScript!
  • 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223]
  • 5-HT2A receptor in Rat [GtoPdb: 6] [UniProtKB: P14842]
  • 8.7
46 CHEMBL71_lig_chart_46 Serotonin 2a (5-HT2a) receptor HumanRat
There should be some charts here, you may need to enable JavaScript!
  • 5-HT2B receptor/Serotonin 2b (5-HT2b) receptor in Human [ChEMBL: CHEMBL1833] [GtoPdb: 7] [UniProtKB: P41595]
  • 7.28
47 CHEMBL71_lig_chart_47 Serotonin 2b (5-HT2b) receptor Human
There should be some charts here, you may need to enable JavaScript!
  • 5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335]
  • 7.55
48 CHEMBL71_lig_chart_48 Serotonin 2c (5-HT2c) receptor Human
There should be some charts here, you may need to enable JavaScript!
  • 5-HT6 receptor/Serotonin 6 (5-HT6) receptor in Human [ChEMBL: CHEMBL3371] [GtoPdb: 11] [UniProtKB: P50406]
  • 5-HT6 receptor in Rat [GtoPdb: 11] [UniProtKB: P31388]
  • 8.4
49 CHEMBL71_lig_chart_49 Serotonin 6 (5-HT6) receptor HumanRat
There should be some charts here, you may need to enable JavaScript!
  • 5-HT7 receptor/Serotonin 7 (5-HT7) receptor in Human [ChEMBL: CHEMBL3155] [GtoPdb: 12] [UniProtKB: P34969]
  • 5-HT7 receptor in Mouse [GtoPdb: 12] [UniProtKB: P32304]
  • 5-HT7 receptor/Serotonin 7 (5-HT7) receptor in Rat [ChEMBL: CHEMBL3223] [GtoPdb: 12] [UniProtKB: P32305]
  • 7.64
50 CHEMBL71_lig_chart_50 Serotonin 7 (5-HT7) receptor HumanMouseRat
There should be some charts here, you may need to enable JavaScript!