desmopressin   Click here for help

GtoPdb Ligand ID: 2182

Synonyms: 1-deamino,D-AVP | [deamino-Cys1,D-Arg8]vasopressin | dDAVP | Noctiva®
Approved drug
desmopressin is an approved drug (FDA (1978))
Compound class: Peptide
Comment: Synthetic analogue of AVP. As is the case with many peptide molecules, there is ambiguity in the stereochemistry of the chemical structure of desmopressin. The structure shown here does not specify stereochemistry and so may vary from the representations shown on other resources linked to from the table above. PubChem also includes the following structures for desmopressin: (CID 16051933 and CID 5311065).
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2D Structure
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Canonical SMILES NC(=O)CC1NC(=O)C(CCC(=O)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)CCSSCC(NC1=O)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)N)CCCN=C(N)N)Cc1ccc(cc1)O
Isomeric SMILES NC(=O)CC1NC(=O)C(CCC(=O)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)CCSSCC(NC1=O)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)N)CCCN=C(N)N)Cc1ccc(cc1)O
InChI InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)
Classification Click here for help
Compound class Peptide
Approved drug? Yes (FDA (1978))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
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IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
3799 desmopressin
Synonyms Click here for help
1-deamino,D-AVP | [deamino-Cys1,D-Arg8]vasopressin | dDAVP | Noctiva®
Database Links Click here for help
Specialist databases
GPCRdb Ligand desmopressin
Other databases
CAS Registry No. 16679-58-6 (source: Scifinder)
ChEMBL Ligand CHEMBL264448
DrugBank Ligand DB00035
GtoPdb PubChem SID 135652102
PubChem CID 27991
Search Google for chemical match using the InChIKey NFLWUMRGJYTJIN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NFLWUMRGJYTJIN
Search PubMed clinical trials desmopressin
Search PubMed titles desmopressin
Search PubMed titles/abstracts desmopressin
UniChem Compound Search for chemical match using the InChIKey NFLWUMRGJYTJIN-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey NFLWUMRGJYTJIN-UHFFFAOYSA-N
Wikipedia Desmopressin