naporafenib [Ligand Id: 10658] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619] | ||||||||
| GtoPdb | Binding affinity determined using the KinomeScan® platform. | - | 7.85 | pKd | 14 | nM | Kd | J Med Chem (2020) 63: 2013-2027 [PMID:31059256] |
| discoidin domain receptor tyrosine kinase 1 in Human [GtoPdb: 1843] [UniProtKB: Q08345] | ||||||||
| GtoPdb | Binding affinity determined using the KinomeScan® platform. | - | 8.74 | pKd | 1.8 | nM | Kd | J Med Chem (2020) 63: 2013-2027 [PMID:31059256] |
| discoidin domain receptor tyrosine kinase 2 in Human [GtoPdb: 1844] [UniProtKB: Q16832] | ||||||||
| GtoPdb | Binding affinity determined using the KinomeScan® platform. | - | 8 | pKd | 10 | nM | Kd | J Med Chem (2020) 63: 2013-2027 [PMID:31059256] |
| B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056] | ||||||||
| GtoPdb | Binding affinity determined using the KinomeScan® platform. | - | 8.89 | pKd | 1.3 | nM | Kd | J Med Chem (2020) 63: 2013-2027 [PMID:31059256] |
| Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049] | ||||||||
| GtoPdb | Binding affinity determined using the KinomeScan® platform. | - | 8.44 | pKd | 3.6 | nM | Kd | J Med Chem (2020) 63: 2013-2027 [PMID:31059256] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
