GW-5823 [Ligand Id: 865] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL293226 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CCK1 receptor/Cholecystokinin A receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238] | ||||||||
| GtoPdb | - | - | 7.6 | pIC50 | 25.1 | nM | IC50 | J Med Chem (1997) 40: 2706-25 [PMID:9276016] |
| ChEMBL | In vitro for binding affinity against human cholecystokinin type A receptor. | B | 7.64 | pIC50 | 22.91 | nM | IC50 | J Med Chem (1997) 40: 2706-2725 [PMID:9276016] |
| ChEMBL | Binding affinity against human Cholecystokinin type A receptor by displacement of [125I]CCK-8 | B | 7.64 | pIC50 | 22.91 | nM | IC50 | J Med Chem (1996) 39: 2655-2658 [PMID:8709093] |
| CCK2 receptor/Cholecystokinin B receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239] | ||||||||
| GtoPdb | - | - | 6 | pIC50 | - | - | - | J Med Chem (1997) 40: 2706-25 [PMID:9276016] |
| ChEMBL | In vitro for binding affinity against human cholecystokinin type B receptor. | B | 6 | pIC50 | 1000 | nM | IC50 | J Med Chem (1997) 40: 2706-2725 [PMID:9276016] |
| ChEMBL | Binding affinity against human Cholecystokinin type B receptor by displacement of [125I]CCK-8 | B | 6 | pIC50 | 1000 | nM | IC50 | J Med Chem (1996) 39: 2655-2658 [PMID:8709093] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
