GW-5823 [Ligand Id: 865] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL293226
  • CCK1 receptor/Cholecystokinin A receptor in Human [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238]
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  • CCK2 receptor/Cholecystokinin B receptor in Human [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CCK1 receptor/Cholecystokinin A receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238]
GtoPdb - - 7.6 pIC50 25.1 nM IC50 J. Med. Chem. (1997) 40: 2706-25 [PMID:9276016]
ChEMBL In vitro for binding affinity against human cholecystokinin type A receptor. B 7.64 pIC50 22.91 nM IC50 J. Med. Chem. (1997) 40: 2706-2725 [PMID:9276016]
ChEMBL Binding affinity against human Cholecystokinin type A receptor by displacement of [125I]CCK-8 B 7.64 pIC50 22.91 nM IC50 J. Med. Chem. (1996) 39: 2655-2658 [PMID:8709093]
CCK2 receptor/Cholecystokinin B receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239]
GtoPdb - - 6 pIC50 - - - J. Med. Chem. (1997) 40: 2706-25 [PMID:9276016]
ChEMBL In vitro for binding affinity against human cholecystokinin type B receptor. B 6 pIC50 1000 nM IC50 J. Med. Chem. (1997) 40: 2706-2725 [PMID:9276016]
ChEMBL Binding affinity against human Cholecystokinin type B receptor by displacement of [125I]CCK-8 B 6 pIC50 1000 nM IC50 J. Med. Chem. (1996) 39: 2655-2658 [PMID:8709093]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]