efmarodocokin alfa   Click here for help

GtoPdb Ligand ID: 12212

Synonyms: IL-22Fc | RG 7880 | RG7880 | UTTR1147A
Compound class: Antibody
Comment: Efmarodocokin alfa is a recombinant human IL-22-Fc IgG4 fusion protein that acts as an agonist of the heterodimeric Interleukin-22α1/10β receptor which is expressed by epithelial cells. It activates the IL-22 signaling pathway without inducing systemic inflammation or causing immunosuppression. Efmarodocokin alfa was developed for potential to treat infectious or inflammatory diseases [2]. The most advanced investigation of its clinical utility has been of its potential to induce repair of the intestinal epithelial damage that is caused by inflammatory bowel diseases [1].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11266 efmarodocokin alfa
Synonyms Click here for help
IL-22Fc | RG 7880 | RG7880 | UTTR1147A
Database Links Click here for help
GtoPdb PubChem SID 472319332
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