ChEMBL ligand: CHEMBL770 (Tolazoline, Priscoline)
5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Human [ChEMBL: CHEMBL1898] [GtoPdb: 2] [UniProtKB: P28222] 1 CHEMBL770_lig_chart_1 Serotonin 1b (5-HT1b) receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221] 2 CHEMBL770_lig_chart_2 Serotonin 1d (5-HT1d) receptor Human There should be some charts here, you may need to enable JavaScript!
TA1 receptor/Trace amine-associated receptor 1 in Human [ChEMBL: CHEMBL5857] [GtoPdb: 364] [UniProtKB: Q96RJ0] This target only has 1 pki data point 3 CHEMBL770_lig_chart_3 Trace amine-associated receptor 1 Human There should be some charts here, you may need to enable JavaScript!
α2A-adrenoceptor in Human [GtoPdb: 25] [UniProtKB: P08913] This target only has 1 pki data point 4 CHEMBL770_lig_chart_4 α2A-adrenoceptor Human There should be some charts here, you may need to enable JavaScript!
α2B-adrenoceptor in Human [GtoPdb: 26] [UniProtKB: P18089] This target only has 1 pki data point 5 CHEMBL770_lig_chart_5 α2B-adrenoceptor Human There should be some charts here, you may need to enable JavaScript!
α2C-adrenoceptor in Human [GtoPdb: 27] [UniProtKB: P18825] This target only has 1 pki data point 6 CHEMBL770_lig_chart_6 α2C-adrenoceptor Human There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1898] [GtoPdb: 2] [UniProtKB: P28222]
ChEMBL	Binding affinity towards human 5-hydroxytryptamine 1B receptor using [3H]5-HT trifluoroacetate as radioligand	B	5	pKi	>10000	nM	Ki	J. Med. Chem. (1998) 41: 2243-2251 [PMID:9632357]
ChEMBL	Binding affinity towards human 5-hydroxytryptamine 1B receptor	B	5	pKi	>10000	nM	Ki	Bioorg. Med. Chem. Lett. (2004) 14: 4697-4699 [PMID:15324890]
5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221]
ChEMBL	Binding affinity towards human 5-hydroxytryptamine 1D receptor using [3H]5-HT trifluoroacetate as radioligand	B	5	pKi	>10000	nM	Ki	J. Med. Chem. (1998) 41: 2243-2251 [PMID:9632357]
ChEMBL	Binding affinity towards human 5-hydroxytryptamine 1D receptor	B	5	pKi	>10000	nM	Ki	Bioorg. Med. Chem. Lett. (2004) 14: 4697-4699 [PMID:15324890]
TA1 receptor/Trace amine-associated receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5857] [GtoPdb: 364] [UniProtKB: Q96RJ0]
ChEMBL	Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by beta counting analysis	B	5.79	pKi	1640	nM	Ki	Bioorg. Med. Chem. Lett. (2012) 22: 5244-5248 [PMID:22795332]
α2A-adrenoceptor in Human [GtoPdb: 25] [UniProtKB: P08913]
GtoPdb	Inhibition of agonist-stimulated [35S]GTPγS binding	-	6.7	pKi	199	nM	Ki	Biochem. Pharmacol. (1998) 55: 1035-43 [PMID:9605427]
α2B-adrenoceptor in Human [GtoPdb: 26] [UniProtKB: P18089]
GtoPdb	Inhibition of agonist-stimulated [35S]GTPγS binding	-	5.5	pKi	3162	nM	Ki	Biochem. Pharmacol. (1998) 55: 1035-43 [PMID:9605427]
α2C-adrenoceptor in Human [GtoPdb: 27] [UniProtKB: P18825]
GtoPdb	Inhibition of agonist-stimulated [35S]GTPγS binding	-	5.43	pKi	3715	nM	Ki	Biochem. Pharmacol. (1998) 55: 1035-43 [PMID:9605427]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]