ChEMBL ligand: CHEMBL483847
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Human [ChEMBL: CHEMBL1862] [GtoPdb: 1923] [UniProtKB: P00519] ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Mouse [ChEMBL: CHEMBL3099] [GtoPdb: 1923] [UniProtKB: P00520] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1862] [GtoPdb: 1923] [UniProtKB: P00519]
ChEMBL	Inhibition of recombinant human c-ABL SH1 domain expressed in sf9 insect cells after 30 mins in presence of [gamma-32P]ATP by autoradiography	B	5	pIC50	>10000	nM	IC50	J Med Chem (2018) 61: 8120-8135 [PMID:30137981]
ChEMBL	Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assay	B	5.55	pIC50	2800	nM	IC50	ACS Med Chem Lett (2017) 8: 1042-1047 [PMID:29057048]
ChEMBL	Inhibition of recombinant human c-ABL SH3/SH2/SH1 domain (46 to 531 residues) expressed in sf9 insect cells after 30 mins in presence of [gamma-32P]ATP by autoradiography	B	8.05	pIC50	9	nM	IC50	J Med Chem (2018) 61: 8120-8135 [PMID:30137981]
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3099] [GtoPdb: 1923] [UniProtKB: P00520]
ChEMBL	Inhibition of Bcr-Abl T315I mutant in mouse BA/F3 cells assessed as cell growth inhibition	B	5	pEC50	>10000	nM	EC50	J Med Chem (2010) 53: 6934-6946 [PMID:20828158]
ChEMBL	Inhibition of Bcr-Abl E505K mutant in mouse BA/F3 cells assessed as cell growth inhibition	B	5	pEC50	>10000	nM	EC50	J Med Chem (2010) 53: 6934-6946 [PMID:20828158]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]