cefluprenam   Click here for help

GtoPdb Ligand ID: 10777

Synonyms: E-1077 | E1077
Compound class: Synthetic organic
Comment: Cefluprenam (E-1077) is a parenteral cephalosporin antibacterial [2-3]. It exhibits broad in vitro antibacterial activity against gram-positive and gram-negative bacteria.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 259.56
Molecular weight 556.13
XLogP -4.07
No. Lipinski's rules broken 2
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Canonical SMILES FCO/N=C(/c1nsc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])/C=C/C[N+](CC(=O)N)(CC)C
Isomeric SMILES FCO/N=C(/c1nsc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])/C=C/C[N+](CC(=O)N)(CC)C
InChI InChI=1S/C20H25FN8O6S2/c1-3-29(2,7-11(22)30)6-4-5-10-8-36-18-13(17(32)28(18)14(10)19(33)34)24-16(31)12(26-35-9-21)15-25-20(23)37-27-15/h4-5,13,18H,3,6-9H2,1-2H3,(H5-,22,23,24,25,27,30,31,33,34)/b5-4+,26-12-/t13-,18-,29?/m1/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
7245 cefluprenam
Synonyms Click here for help
E-1077 | E1077
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Cefluprenam, E1077
Other databases
CAS Registry No. 116853-25-9 (source: WHO INN record)
ChEMBL Ligand CHEMBL2074822
GtoPdb PubChem SID 405560218
PubChem CID 6536774
Search Google for chemical match using the InChIKey XAKKNLNAJBNLPC-MAYKBZFQSA-N
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UniChem Compound Search for chemical match using the InChIKey XAKKNLNAJBNLPC-MAYKBZFQSA-N
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