sulfasalazine

Ligand id: 4840

Name: sulfasalazine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 149.69
Molecular weight 398.07
XLogP 3.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1950))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid
International Nonproprietary Names
INN number INN
2210 sulfasalazine
Synonyms
Azulfidine® | Salazopyridin® | Salazopyrin® | SAS-500
Comments
Sulfasalazine is sulfa drug derivative of mesalazine, classified as a disease-modifying antirheumatic drug (DMARD).
Sulfasalazine is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Database Links
CAS Registry No. 599-79-1 (source: Scifinder)
ChEMBL Ligand CHEMBL421
DrugBank Ligand DB00795
GtoPdb PubChem SID 178101542
PubChem CID 5384001
RCSB PDB Ligand SAS
Search Google for chemical match using the InChIKey NCEXYHBECQHGNR-QZQOTICOSA-N
Search Google for chemicals with the same backbone NCEXYHBECQHGNR
Search PubMed clinical trials sulfasalazine
Search PubMed titles sulfasalazine
Search PubMed titles/abstracts sulfasalazine
Search UniChem for chemical match using the InChIKey NCEXYHBECQHGNR-QZQOTICOSA-N
Search UniChem for chemicals with the same backbone NCEXYHBECQHGNR
Wikipedia Sulfasalazine