Synonyms: Azulfidine® | Salazopyridin® | Salazopyrin® | SAS-500
sulfasalazine is an approved drug (FDA (1950))
Compound class:
Synthetic organic
Comment: Sulfasalazine is sulfa drug derivative of mesalazine, classified as a disease-modifying antirheumatic drug (DMARD).
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖![]() View more information in the IUPHAR Pharmacology Education Project: sulfasalazine |
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References |
1. Kussmann M, Obermueller M, Spettel K, Winkler S, Aletaha D. (2021)
In vitro evaluation of disease-modifying antirheumatic drugs against rheumatoid arthritis associated pathogens of the oral microflora. RMD Open, 7 (3). [PMID:34588273] |
2. Mushtaq S, Sarkar R. (2020)
Sulfasalazine in dermatology: A lesser explored drug with broad therapeutic potential. Int J Womens Dermatol, 6 (3): 191-198. [PMID:32637543] |
3. Qiu A, Jansen M, Sakaris A, Min SH, Chattopadhyay S, Tsai E, Sandoval C, Zhao R, Akabas MH, Goldman ID. (2006)
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell, 127 (5): 917-28. [PMID:17129779] |