Classification
Compound class	Synthetic organic
Approved drug?	Yes (EMA (2014))

IUPAC Name

3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid

International Nonproprietary Names
INN number	INN
8956	ataluren

Synonyms

PTC124

Comments

Ataluren is a compound in an emerging class of chemicals which induce ribosomal readthrough. This developing pharmaceutical intervention has been termed 'readthrough strategy'. Clinically, this type of compound has potential benefit in the treatment of genetic disorders associated with loss of functional protein due to nonsense or PTC mutations, such as certain types of muscular dystrophy, cystic fibrosis and many cancers [1,4].

Database Links
CAS Registry No.	775304-57-9 (source: SciFinder)
ChEMBL Ligand	CHEMBL256997
GtoPdb PubChem SID	178103913
PubChem CID	11219835
Search Google for chemical match using the InChIKey	OOUGLTULBSNHNF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	OOUGLTULBSNHNF
Search PubMed clinical trials	ataluren
Search PubMed titles	ataluren
Search PubMed titles/abstracts	ataluren
Search UniChem for chemical match using the InChIKey	OOUGLTULBSNHNF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	OOUGLTULBSNHNF
Wikipedia	Ataluren