Synonyms: PTC124
ataluren is an approved drug (EMA (2014))
Compound class:
Synthetic organic
Comment: Ataluren is a compound in an emerging class of chemicals which induce ribosomal readthrough. This developing pharmaceutical intervention has been termed 'readthrough strategy'. Clinically, this type of compound has potential benefit in the treatment of genetic disorders associated with loss of functional protein due to nonsense or PTC mutations, such as certain types of muscular dystrophy, cystic fibrosis and many cancers [1,4].
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (EMA (2014)) |
IUPAC Name ![]() |
3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid |
International Nonproprietary Names ![]() |
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INN number | INN |
8956 | ataluren |
Synonyms ![]() |
PTC124 |
Database Links ![]() |
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CAS Registry No. | 775304-57-9 (source: SciFinder) |
ChEMBL Ligand | CHEMBL256997 |
DrugCentral Ligand | 4872 |
GtoPdb PubChem SID | 178103913 |
PubChem CID | 11219835 |
Search Google for chemical match using the InChIKey | OOUGLTULBSNHNF-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | OOUGLTULBSNHNF |
Search PubMed clinical trials | ataluren |
Search PubMed titles | ataluren |
Search PubMed titles/abstracts | ataluren |
Search UniChem for chemical match using the InChIKey | OOUGLTULBSNHNF-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | OOUGLTULBSNHNF |
Wikipedia | Ataluren |