BMS compound 87b [Ligand Id: 3492] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL50593 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CCR3/C-C chemokine receptor type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3473] [GtoPdb: 60] [UniProtKB: P51677] | ||||||||
| GtoPdb | - | - | 8.1 | pKi | 7.94 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 1785-9 [PMID:12067561] |
| ChEMBL | In vitro C-C chemokine receptor type 3 activity of compound by using eotaxin induced human eosinophil chemotaxis assay | F | 7.7 | pIC50 | 20 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1785-1789 [PMID:12067561] |
| ChEMBL | In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxin | B | 8.1 | pIC50 | 8 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1785-1789 [PMID:12067561] |
| ChEMBL | In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxin | B | 8.22 | pIC50 | 6 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1785-1789 [PMID:12067561] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
