(-)-methadone   Click here for help

GtoPdb Ligand ID: 1605

Synonyms: (R)-methadone | l-methadone | levomethadone
Compound class: Synthetic organic
Comment: (-)-methadone is a component of the approved drug methadone, and while it has been assigned an INN, it is not itself an approved drug. See our ligand entry for methadone for futher details.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 20.31
Molecular weight 309.21
XLogP 4.59
No. Lipinski's rules broken 0
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Canonical SMILES CCC(=O)C(c1ccccc1)(c1ccccc1)CC(N(C)C)C
Isomeric SMILES CCC(=O)C(c1ccccc1)(c1ccccc1)C[C@H](N(C)C)C
InChI InChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3/t17-/m1/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
5002 levomethadone
788 methadone
Synonyms Click here for help
(R)-methadone | l-methadone | levomethadone
Database Links Click here for help
Specialist databases
GPCRdb Ligand (-)-methadone
Other databases
CAS Registry No. 125-58-6 (source: Scifinder)
ChEMBL Ligand CHEMBL159659
DrugBank Ligand DB00333
DrugCentral Ligand 4586
GtoPdb PubChem SID 135650582
PubChem CID 22267
Search Google for chemical match using the InChIKey USSIQXCVUWKGNF-QGZVFWFLSA-N
Search Google for chemicals with the same backbone USSIQXCVUWKGNF
Search PubMed clinical trials methadone
Search PubMed titles methadone
Search PubMed titles/abstracts methadone
UniChem Compound Search for chemical match using the InChIKey USSIQXCVUWKGNF-QGZVFWFLSA-N
UniChem Connectivity Search for chemical match using the InChIKey USSIQXCVUWKGNF-QGZVFWFLSA-N
Wikipedia Methadone