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ChEMBL ligand: CHEMBL155625 (Indole 3-carbinol, Indole-3-carbinol, NSC-525801) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Aryl hydrocarbon receptor in Mouse [GtoPdb: 2951] [UniProtKB: P30561] | ||||||||
GtoPdb | Radioligand displacement binding of [2-1251]7,8-dibromodibenzo-pdioxin to AhR prepared from C57BL/6J mouse liver cytosol. | - | 4.57 | pKd | 27000 | nM | Kd | Proc Natl Acad Sci USA (1991) 88: 9543-7 [PMID:1658785] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]