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ChEMBL ligand: CHEMBL534232 (BRL-15572) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay | F | 5 | pIC50 | 10000 | nM | IC50 | Nat Chem Biol (2009) 5: 765-771 [PMID:19734910] |
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
GtoPdb | - | - | 7.7 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
GtoPdb | - | - | 6.1 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
GtoPdb | - | - | 7.9 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566] | ||||||||
GtoPdb | - | - | 5.2 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939] | ||||||||
GtoPdb | - | - | 6 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
GtoPdb | - | - | 6.6 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595] | ||||||||
GtoPdb | - | - | 7.4 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335] | ||||||||
GtoPdb | - | - | 6.2 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406] | ||||||||
GtoPdb | - | - | 5.9 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]