ChEMBL ligand: CHEMBL534232 (BRL-15572)
Plasmodium falciparum [ChEMBL: CHEMBL364] This target only has 0 pki data point 1 CHEMBL534232_lig_chart_1 Plasmodium falciparum Plasmodium falciparum There should be some charts here, you may need to enable JavaScript!
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908] This target only has 1 pki data point 2 CHEMBL534232_lig_chart_2 5-HT1A receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] This target only has 1 pki data point 3 CHEMBL534232_lig_chart_3 5-HT1B receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221] This target only has 1 pki data point 4 CHEMBL534232_lig_chart_4 5-HT1D receptor Human There should be some charts here, you may need to enable JavaScript!
5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566] This target only has 1 pki data point 5 CHEMBL534232_lig_chart_5 5-ht1e receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939] This target only has 1 pki data point 6 CHEMBL534232_lig_chart_6 5-HT1F receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223] This target only has 1 pki data point 7 CHEMBL534232_lig_chart_7 5-HT2A receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595] This target only has 1 pki data point 8 CHEMBL534232_lig_chart_8 5-HT2B receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335] This target only has 1 pki data point 9 CHEMBL534232_lig_chart_9 5-HT2C receptor Human There should be some charts here, you may need to enable JavaScript!
5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406] This target only has 1 pki data point 10 CHEMBL534232_lig_chart_10 5-HT6 receptor Human There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay	F	5	pIC50	10000	nM	IC50	Nat. Chem. Biol. (2009) 5: 765-771 [PMID:19734910]
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
GtoPdb	-	-	7.7	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222]
GtoPdb	-	-	6.1	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221]
GtoPdb	-	-	7.9	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566]
GtoPdb	-	-	5.2	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939]
GtoPdb	-	-	6	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
GtoPdb	-	-	6.6	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
GtoPdb	-	-	7.4	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335]
GtoPdb	-	-	6.2	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]
5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406]
GtoPdb	-	-	5.9	pKi	-	-	-	Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]