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ChEMBL ligand: CHEMBL534232 (BRL-15572) |
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2
CHEMBL534232_lig_chart_2
5-HT1A receptor
Human
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3
CHEMBL534232_lig_chart_3
5-HT1B receptor
Human
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4
CHEMBL534232_lig_chart_4
5-HT1D receptor
Human
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5
CHEMBL534232_lig_chart_5
5-ht1e receptor
Human
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6
CHEMBL534232_lig_chart_6
5-HT1F receptor
Human
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7
CHEMBL534232_lig_chart_7
5-HT2A receptor
Human
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8
CHEMBL534232_lig_chart_8
5-HT2B receptor
Human
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9
CHEMBL534232_lig_chart_9
5-HT2C receptor
Human
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10
CHEMBL534232_lig_chart_10
5-HT6 receptor
Human
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay | F | 5 | pIC50 | 10000 | nM | IC50 | Nat. Chem. Biol. (2009) 5: 765-771 [PMID:19734910] |
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
GtoPdb | - | - | 7.7 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
GtoPdb | - | - | 6.1 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
GtoPdb | - | - | 7.9 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566] | ||||||||
GtoPdb | - | - | 5.2 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939] | ||||||||
GtoPdb | - | - | 6 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
GtoPdb | - | - | 6.6 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595] | ||||||||
GtoPdb | - | - | 7.4 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335] | ||||||||
GtoPdb | - | - | 6.2 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406] | ||||||||
GtoPdb | - | - | 5.9 | pKi | - | - | - | Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356: 312-20 [PMID:9303567] |
ChEMBL data shown on this page come from version 27:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]