Synonyms: PX-866 | PX866
Compound class:
Synthetic organic
Comment: Sonolisib is a small-molecule wortmannin inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity [1]. It is compound 4 in Zask et al. (2008) [3].
|
|
Classification ![]() |
|
Compound class | Synthetic organic |
IUPAC Name ![]() |
[(3aR,6E,9S,9aR,10R,11aS)-6-[(di(prop-2-enyl)amino)methylidene]-5-hydroxy-9-(methoxymethyl)-9a,11a-dimethyl-1,4,7-trioxo-2,3,3a,9,10,11-hexahydroindeno[7,6-h]isochromen-10-yl] acetate |
International Nonproprietary Names ![]() |
|
INN number | INN |
9630 | sonolisib |
Synonyms ![]() |
PX-866 | PX866 |
Database Links ![]() |
|
Specialist databases | |
Reactome Drug
![]() |
R-ALL-2399860 |
Reactome Reaction
![]() |
R-HSA-2400009 |
Other databases | |
CAS Registry No. | 502632-66-8 |
ChEBI | CHEBI:65345 |
ChEMBL Ligand | CHEMBL411907 |
GtoPdb PubChem SID | 249565624 |
PubChem CID | 9849735 |
Search Google for chemical match using the InChIKey | QIUASFSNWYMDFS-NILGECQDSA-N |
Search Google for chemicals with the same backbone | QIUASFSNWYMDFS |
Search PubMed clinical trials | sonolisib |
Search PubMed titles | sonolisib |
Search PubMed titles/abstracts | sonolisib |
UniChem Compound Search for chemical match using the InChIKey | QIUASFSNWYMDFS-NILGECQDSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | QIUASFSNWYMDFS-NILGECQDSA-N |
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
✖
Sonolisib (links to external site)
Cat. No. HY-N6775 |