aciclovir [Ligand Id: 4829] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL184 (Soraway, Soothelip, Viralief, Virovir 400, Cymex Ultra, Acyclovir, Herpetad, Lipsore, Virasorb, Avert, Clearsore, Aviral, Sitavig, Virovir 200, Zovirax, Aciclovir, NSC-645011, Cyclovir, Duvimex, Ranovir, Lypsyl, Avaclyr, Acycloguanosine, Virovir 800)
  • Purine nucleoside phosphorylase in Mycobacterium tuberculosis [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01]
  • This target only has 0 pki data point
1 CHEMBL184_lig_chart_1 Purine nucleoside phosphorylase Mycobacterium tuberculosis
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Purine nucleoside phosphorylase in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01]
ChEMBL Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysis B 4.9 pKd 12589.25 nM Kd Bioorg. Med. Chem. (2010) 18: 4769-4774 [PMID:20570524]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]