ChEMBL ligand: CHEMBL184 (Aciclovir, Aciclovirum, Acycloguanosine, Acyclovir, Avaclyr, Avert, Aviral, Clearsore, Cyclovir, Cymex ultra, Duvimex, Gerpevir, Herpetad, Lipsore, Lypsyl, Novirus, NSC-645011, NSC-758477, Ranovir, Sitavig, Soothelip, Soraway, Viralief, Virasorb, Virovir 200, Virovir 400, Virovir 800, Zovirax)
Purine nucleoside phosphorylase in Mycobacterium tuberculosis [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01] purine nucleoside phosphorylase/Purine nucleoside phosphorylase in Human [ChEMBL: CHEMBL4338] [GtoPdb: 2841] [UniProtKB: P00491] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Purine nucleoside phosphorylase in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01]
ChEMBL	Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysis	B	4.9	pKd	12589.25	nM	Kd	Bioorg. Med. Chem. (2010) 18: 4769-4774 [PMID:20570524]
purine nucleoside phosphorylase/Purine nucleoside phosphorylase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4338] [GtoPdb: 2841] [UniProtKB: P00491]
ChEMBL	Inhibition of human PNP	B	4.04	pKi	91000	nM	Ki	MedChemComm (2018) 9: 1983-1993 [PMID:30627387]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]