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ChEMBL ligand: CHEMBL184 (Soraway, Soothelip, Viralief, Virovir 400, Cymex Ultra, Acyclovir, Herpetad, Lipsore, Virasorb, Avert, Clearsore, Aviral, Sitavig, Virovir 200, Zovirax, Aciclovir, NSC-645011, Cyclovir, Duvimex, Ranovir, Lypsyl, Avaclyr, Acycloguanosine, Virovir 800) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Purine nucleoside phosphorylase in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01] | ||||||||
ChEMBL | Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysis | B | 4.9 | pKd | 12589.25 | nM | Kd | Bioorg. Med. Chem. (2010) 18: 4769-4774 [PMID:20570524] |
ChEMBL data shown on this page come from version 27:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]