ChEMBL ligand: CHEMBL1360 (Atracurium, Tracrium)
KCa2.3/Small conductance calcium-activated potassium channel protein 3 in Rat [ChEMBL: CHEMBL3780] [GtoPdb: 383] [UniProtKB: P70605] This target only has 1 pki data point 1 CHEMBL1360_lig_chart_1 Small conductance calcium-activated potassium channel protein 3 Rat There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor α1 subunit in Human [GtoPdb: 462] [UniProtKB: P02708] This target only has 0 pki data point 2 CHEMBL1360_lig_chart_2 nicotinic acetylcholine receptor α1 subunit Human There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor α3 subunit in Human [GtoPdb: 464] [UniProtKB: P32297] This target only has 0 pki data point 3 CHEMBL1360_lig_chart_3 nicotinic acetylcholine receptor α3 subunit Human There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor α4 subunit in Human [GtoPdb: 465] [UniProtKB: P43681] This target only has 0 pki data point 4 CHEMBL1360_lig_chart_4 nicotinic acetylcholine receptor α4 subunit Human There should be some charts here, you may need to enable JavaScript!
nicotinic acetylcholine receptor α7 subunit in Human [GtoPdb: 468] [UniProtKB: P36544] This target only has 0 pki data point 5 CHEMBL1360_lig_chart_5 nicotinic acetylcholine receptor α7 subunit Human There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
KCa2.3/Small conductance calcium-activated potassium channel protein 3 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3780] [GtoPdb: 383] [UniProtKB: P70605]
ChEMBL	Inhibition of Wistar rat recombinant SK3 channel expressed in HEK293 cells by whole cell patch clamp technique	B	5.19	pKd	6400	nM	Kd	J. Med. Chem. (2008) 51: 7625-7634 [PMID:18998663]
ChEMBL	Displacement of [I125]apamine from Wistar rat recombinant SK3 channel expressed in HEK293 cells	B	5.23	pKi	5900	nM	Ki	J. Med. Chem. (2008) 51: 7625-7634 [PMID:18998663]
nicotinic acetylcholine receptor α1 subunit in Human [GtoPdb: 462] [UniProtKB: P02708]
GtoPdb	Antagonism of ACh activation of α1β1εδ nACh receptors expressed in Xenopus oocytes.	-	7.01	pIC50	97	nM	IC50	Anesthesiology (2006) 105: 521-33 [PMID:16931985]
nicotinic acetylcholine receptor α3 subunit in Human [GtoPdb: 464] [UniProtKB: P32297]
GtoPdb	Antagonism of ACh activation of human α3β2 or α3β4 nACh receptors expressed in Xenopus oocytes, at different ACh concentrations.	-	9.05	pIC50	0.9	nM	IC50	Anesthesiology (2006) 105: 521-33 [PMID:16931985]
nicotinic acetylcholine receptor α4 subunit in Human [GtoPdb: 465] [UniProtKB: P43681]
GtoPdb	Antagonism of ACh activation of human α4β2 nACh receptors expressed in Xenopus oocytes, at different ACh concentrations.	-	8.1	pIC50	7.9	nM	IC50	Anesthesiology (2006) 105: 521-33 [PMID:16931985]
nicotinic acetylcholine receptor α7 subunit in Human [GtoPdb: 468] [UniProtKB: P36544]
GtoPdb	Antagonism of ACh activation of human α7 nACh receptors expressed in Xenopus oocytes, at different ACh concentrations.	-	8.25	pIC50	5.6	nM	IC50	Anesthesiology (2006) 105: 521-33 [PMID:16931985]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]