ChEMBL ligand: CHEMBL120526 (Methanandamide, (R)-Methanandamide)
CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] There should be some charts here, you may need to enable JavaScript!
CB2 receptor/Cannabinoid CB2 receptor in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972] CB2 receptor/Cannabinoid CB2 receptor in Mouse [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936] There should be some charts here, you may need to enable JavaScript!
K2P3.1/Potassium channel subfamily K member 3 in Human [ChEMBL: CHEMBL2321613] [GtoPdb: 515] [UniProtKB: O14649] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL	Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes in absence of FAAH inhibitor PMSF by radioligand binding assay	B	7.14	pKi	72	nM	Ki	J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
ChEMBL	Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes in presence of FAAH inhibitor PMSF by radioligand binding assay	B	7.43	pKi	37	nM	Ki	J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
ChEMBL	Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the absence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]CP-55940 as radioligand	B	7.55	pKi	28.3	nM	Ki	J Med Chem (1998) 41: 5353-5361 [PMID:9876105]
ChEMBL	Tested for binding affinity to Cannabinoid receptor 1	B	7.7	pKi	20	nM	Ki	J Med Chem (1999) 42: 896-902 [PMID:10072686]
ChEMBL	Displacement of [3H]CP-55940 from Cannabinoid receptor 1 of rat forebrain membranes	B	7.7	pKi	20	nM	Ki	J Med Chem (1996) 39: 4515-4519 [PMID:8893848]
ChEMBL	Displacement of [3H]-CP55940 from CB1 receptor of rat cerebellar membranes by liquid scintillation counting in presence of serine protease inhibitor PMSF	B	7.7	pKi	20	nM	Ki	J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
GtoPdb	-	-	7.7	pKi	20	nM	Ki	J Med Chem (1996) 39: 4515-9 [PMID:8893848]
ChEMBL	Displacement of [3H]CP-55940 from cannabinoid CB1 receptor in rat brain membrane in presence of phenylmethanesulfonyl fluoride	B	7.75	pKi	17.9	nM	Ki	Bioorg Med Chem Lett (2008) 18: 5912-5915 [PMID:18723350]
ChEMBL	Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]CP-55940 as radioligand	B	7.75	pKi	17.9	nM	Ki	J Med Chem (1998) 41: 5353-5361 [PMID:9876105]
CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL	Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cell membranes in absence of FAAH inhibitor PMSF by radioligand binding assay	B	6.66	pKi	220	nM	Ki	J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
CB2 receptor/Cannabinoid CB2 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
ChEMBL	Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cell membranes in absence of FAAH inhibitor PMSF by radioligand binding assay	B	6	pKi	>1000	nM	Ki	J Med Chem (2018) 61: 8639-8657 [PMID:30196704]
ChEMBL	Binding affinity towards Cannabinoid receptor 2 from mouse spleen membranes using 0.8 nM [3H]CP-55940 as radioligand	B	6.06	pKi	868	nM	Ki	J Med Chem (1998) 41: 5353-5361 [PMID:9876105]
ChEMBL	Displacement of [3H]CP-55940 from cannabinoid CB2 receptor in mouse spleen membrane	B	6.06	pKi	868	nM	Ki	Bioorg Med Chem Lett (2008) 18: 5912-5915 [PMID:18723350]
ChEMBL	Compound was evaluated for its binding affinity for mouse spleen Cannabinoid receptor 2	B	6.09	pKi	815	nM	Ki	J Med Chem (1996) 39: 4515-4519 [PMID:8893848]
ChEMBL	Binding affinity to mouse spleen CB2 receptor	B	6.09	pKi	815	nM	Ki	J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
K2P3.1/Potassium channel subfamily K member 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2321613] [GtoPdb: 515] [UniProtKB: O14649]
GtoPdb	-	-	6.15	pIC50	~700	nM	IC50	EMBO J (2001) 20: 47-54 [PMID:11226154]
ChEMBL	Inhibition of human TASK1 expressed in African green monkey COS cells by whole cell patch clamp assay	B	7	pIC50	100	nM	IC50	J Med Chem (2019) 62: 10044-10058 [PMID:31260312]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]