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ChEMBL ligand: CHEMBL2311103 (ORG-2058) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Progesterone receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401] | ||||||||
ChEMBL | Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 310K | B | 8.27 | pKd | 5.42 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]ORG2058 at human progesterone receptor at 308 K | B | 8.34 | pKd | 4.56 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]ORG2058 at human progesterone receptor at 303 K | B | 8.38 | pKd | 4.13 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]ORG2058 at human progesterone receptor at 273 K | B | 8.48 | pKd | 3.28 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]ORG2058 at human progesterone receptor at 298 K | B | 8.5 | pKd | 3.16 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 278 K | B | 8.57 | pKd | 2.7 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]ORG2058 at human progesterone receptor at 293K | B | 8.58 | pKd | 2.64 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 283 K | B | 8.6 | pKd | 2.49 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL | Dissociation constant for [3H]ORG2058 at human progesterone receptor at 288 K | B | 8.63 | pKd | 2.32 | nM | Kd | J. Med. Chem. (2005) 48: 2026-2035 [PMID:15771445] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]